Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a006282m |
Family | GT47 |
Protein Properties | Length: 450 Molecular Weight: 51256.7 Isoelectric Point: 9.6476 |
Chromosome | Chromosome/Scaffold: 2 Start: 1204389 End: 1206375 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 84 | 385 | 0 |
KGMKVYVYDLPSKYNADWLSTNQRCGSHLFASEVAIHRALLRSDVVRTLDPWLADFFFVPVYVSCNFSAVNGFPAIGHARPLIAAAVDHVSTQLPFWNRS RGADHVFVASHDFGSCFHTLEDVAIADGVPEFLRNSIVLQTFGVTHKHPCQEVENVVIPPYIPPESVRATLEKFPMTGRRDIFSFFRGKMELHPKNVSGR FYSKRVRTELWRKYGNDRRFYLRRQRFAGYQSEIARSKFCLCPLGWAPWSPRLVESVALGCVPVIIADGIRLPFPSAVPWAEISLTVAENDVDSLGDILE HV |
Full Sequence |
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Protein Sequence Length: 450 Download |
MRRLLHGTRN NRSSDNNGGF FFFCYRYFKW ILWFSISFYF FSSFLNNPTS TSIISRTTVY 60 RTKLASRALI EQSFVNSSHG VLFKGMKVYV YDLPSKYNAD WLSTNQRCGS HLFASEVAIH 120 RALLRSDVVR TLDPWLADFF FVPVYVSCNF SAVNGFPAIG HARPLIAAAV DHVSTQLPFW 180 NRSRGADHVF VASHDFGSCF HTLEDVAIAD GVPEFLRNSI VLQTFGVTHK HPCQEVENVV 240 IPPYIPPESV RATLEKFPMT GRRDIFSFFR GKMELHPKNV SGRFYSKRVR TELWRKYGND 300 RRFYLRRQRF AGYQSEIARS KFCLCPLGWA PWSPRLVESV ALGCVPVIIA DGIRLPFPSA 360 VPWAEISLTV AENDVDSLGD ILEHVAATNL TSIQRNLWDP SVRKSLLFDV PILEGDATWQ 420 VLKALAQMLD RSHKKPSDKN VFSTSENEK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-72 | 84 | 382 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33322.1 | 0 | 23 | 434 | 19 | 435 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
GenBank | ABI64067.1 | 0 | 23 | 434 | 19 | 435 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
RefSeq | XP_002275679.1 | 0 | 3 | 430 | 18 | 441 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002314302.1 | 0 | 23 | 434 | 39 | 455 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523710.1 | 0 | 3 | 434 | 19 | 454 | transferase, putative [Ricinus communis] |