Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a006324m |
Family | GT47 |
Protein Properties | Length: 449 Molecular Weight: 51064.5 Isoelectric Point: 9.0426 |
Chromosome | Chromosome/Scaffold: 90 Start: 690462 End: 693750 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 123 | 399 | 0 |
KTLKIYAYPHDKDDPFANVLLPVNSEPTGNYASESYFKNALFESHFLTNDPSEADLFYLPFSIASLRHDKRVGVGGIKDFVANYVDEISRSYPFWNRSGG ADHFYVACHSVGRTAMEKAVGVKLNAIQVVCSSSYFLSGYVAHKDASIPQIWPRKGVPPTRSPSQRKTLAFYAGAMNSRVRKDLVKTWENDSDISVHYSR LQTPYSEALLGSKFCIHAKGFEVNTARIGDALYYGCVPVVLADYYDLPYSDVINWNRFSVVLSAADIPMLKKILEGI |
Full Sequence |
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Protein Sequence Length: 449 Download |
MAVVISKRRG LFFLPILLSF TSSLFLFLFM ISSTSKPDIL QPGLTRIHVI NPLPEFSTTS 60 SPVMPKQSIV VNRSLVLDLQ TTQLPSRTTQ LASTAETKVE TNDDDDIFHD RSFFTKDYKQ 120 MNKTLKIYAY PHDKDDPFAN VLLPVNSEPT GNYASESYFK NALFESHFLT NDPSEADLFY 180 LPFSIASLRH DKRVGVGGIK DFVANYVDEI SRSYPFWNRS GGADHFYVAC HSVGRTAMEK 240 AVGVKLNAIQ VVCSSSYFLS GYVAHKDASI PQIWPRKGVP PTRSPSQRKT LAFYAGAMNS 300 RVRKDLVKTW ENDSDISVHY SRLQTPYSEA LLGSKFCIHA KGFEVNTARI GDALYYGCVP 360 VVLADYYDLP YSDVINWNRF SVVLSAADIP MLKKILEGIV NRGEYLRMQR NVMRVQKHFQ 420 WHDLPLDFDA FYMVMYELWL RRSHVRIT* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-71 | 121 | 399 | 296 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABD28410.1 | 0 | 34 | 447 | 67 | 481 | Exostosin-like [Medicago truncatula] |
EMBL | CBI39073.1 | 0 | 107 | 447 | 106 | 445 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265438.1 | 0 | 80 | 447 | 75 | 443 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325425.1 | 0 | 121 | 448 | 1 | 323 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002525728.1 | 0 | 121 | 447 | 1 | 326 | catalytic, putative [Ricinus communis] |