Basic Information | |
---|---|
Species | Mimulus guttatus |
Cazyme ID | mgv1a006806m |
Family | GT47 |
Protein Properties | Length: 431 Molecular Weight: 49236.7 Isoelectric Point: 9.5073 |
Chromosome | Chromosome/Scaffold: 79 Start: 119247 End: 121873 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 97 | 381 | 0 |
ERRFKVWTYKEGEPPLFHMGRMKGIYSMEGHMIDALEDSHNQFVAADPAEAHAFFLPVGVAEIIHFLYTPRINYNRNHLHRVVADYVTVVANKYPFWNRS SGADHFFLACHDWGPDVSSANPELYKNFIRGLCNANVSEGFRPNRDVSLPEINVPPGLALGPPDLNKSPNNRTILAFFSGGAHGHVREKLFRHWKERDDE IQVHEYLPKNENYFELMSRSKYCLCPSGYEVASPRLIESMHAGCVPVIVSDGYALPFSDVLDWRRFSVHVPVERIAEIKKILKGI |
Full Sequence |
---|
Protein Sequence Length: 431 Download |
MGSAASLSSP LLLYSCLLLI LIFSCLNAHF HFLPISSSVI STHKQVHKNG NLEKLEQGLA 60 RARAAINKAG RKNASFIPSG SIYRNPYAFH QSYTEMERRF KVWTYKEGEP PLFHMGRMKG 120 IYSMEGHMID ALEDSHNQFV AADPAEAHAF FLPVGVAEII HFLYTPRINY NRNHLHRVVA 180 DYVTVVANKY PFWNRSSGAD HFFLACHDWG PDVSSANPEL YKNFIRGLCN ANVSEGFRPN 240 RDVSLPEINV PPGLALGPPD LNKSPNNRTI LAFFSGGAHG HVREKLFRHW KERDDEIQVH 300 EYLPKNENYF ELMSRSKYCL CPSGYEVASP RLIESMHAGC VPVIVSDGYA LPFSDVLDWR 360 RFSVHVPVER IAEIKKILKG IPMDVYLRKQ KQVLKVKRHF VFNRPSQPYD LMHMILHSLW 420 LRRLNVRLLT * |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-68 | 96 | 381 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21065.1 | 0 | 45 | 428 | 8 | 400 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197526.4 | 0 | 35 | 428 | 5 | 407 | catalytic [Arabidopsis thaliana] |
Swiss-Prot | Q3E9A4 | 0 | 35 | 428 | 63 | 465 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
RefSeq | XP_002515488.1 | 0 | 6 | 428 | 16 | 468 | catalytic, putative [Ricinus communis] |
RefSeq | XP_002531945.1 | 0 | 34 | 428 | 58 | 450 | catalytic, putative [Ricinus communis] |