| Basic Information | |
|---|---|
| Species | Mimulus guttatus |
| Cazyme ID | mgv1a007008m |
| Family | CE10 |
| Protein Properties | Length: 423 Molecular Weight: 46817.8 Isoelectric Point: 8.4025 |
| Chromosome | Chromosome/Scaffold: 11 Start: 690219 End: 693535 |
| Description | prenylcysteine methylesterase |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE10 | 123 | 387 | 0 |
| QVRRSVVYGDQPRNRLDLYLPTNTDELKPVVIFVTGGAWIIGYKAWGSLLGLHLAERDIIVACIDYRNFPQGTISDMVNDVSQGIAFICNNIIEFGGDPN KIYLMGQSAGAHVSACALLQQAVKESRGESISWSMSQINAYFGLSGGYNLLKLVDHFHGRGLYRSIFLSIMEGEKGMEQFSPEIIVQNPGISSAVSLLPR IILFHGTSDYSIPSHASKIFVNTLRKVGAQADLILYDGKTHTDLFLQDPLRGGKDELFDYLIGFI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 423 Download |
| METSSSLPAI FPSTDEITEE AETVSLVRVS SLPSGFSSQQ RRRRVGNNTA SSLGALPRRQ 60 QFSREIGHAA AETYLLTRLS FKLLTYLGVG YRWITRLLAL ALYAMLLMPG FLQVAYDYFF 120 SSQVRRSVVY GDQPRNRLDL YLPTNTDELK PVVIFVTGGA WIIGYKAWGS LLGLHLAERD 180 IIVACIDYRN FPQGTISDMV NDVSQGIAFI CNNIIEFGGD PNKIYLMGQS AGAHVSACAL 240 LQQAVKESRG ESISWSMSQI NAYFGLSGGY NLLKLVDHFH GRGLYRSIFL SIMEGEKGME 300 QFSPEIIVQN PGISSAVSLL PRIILFHGTS DYSIPSHASK IFVNTLRKVG AQADLILYDG 360 KTHTDLFLQD PLRGGKDELF DYLIGFIHAN DKEALAKDAM APPRRRFVPE ILLRLAGKVS 420 PF* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00312 | Esterase_lipase | 6.0e-9 | 138 | 246 | 123 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| pfam07859 | Abhydrolase_3 | 1.0e-9 | 153 | 363 | 217 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| pfam00135 | COesterase | 6.0e-11 | 140 | 241 | 128 | + Carboxylesterase family. | ||
| COG2272 | PnbA | 2.0e-12 | 138 | 241 | 118 | + Carboxylesterase type B [Lipid metabolism] | ||
| COG0657 | Aes | 2.0e-23 | 125 | 363 | 246 | + Esterase/lipase [Lipid metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABD96862.1 | 0 | 11 | 422 | 13 | 427 | hypothetical protein [Cleome spinosa] |
| GenBank | ABK28542.1 | 0 | 41 | 422 | 41 | 422 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_186890.2 | 0 | 41 | 422 | 41 | 422 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_197090.2 | 0 | 1 | 422 | 5 | 427 | ATPCME (PRENYLCYSTEINE METHYLESTERASE); prenylcysteine methylesterase [Arabidopsis thaliana] |
| RefSeq | XP_002264962.1 | 0 | 58 | 422 | 52 | 417 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1jmy_A | 0.00000003 | 122 | 264 | 67 | 235 | A Chain A, Truncated Recombinant Human Bile Salt Stimulated Lipase |
| PDB | 1lzl_A | 0.00000004 | 99 | 242 | 29 | 172 | A Chain A, Bacterial Heroin Esterase |
| PDB | 1lzk_A | 0.00000004 | 99 | 242 | 29 | 172 | A Chain A, Bacterial Heroin Esterase Complex With Transition State Analog Dimethylarsenic Acid |
| PDB | 1f6w_A | 0.0000001 | 122 | 264 | 67 | 235 | A Chain A, Structure Of The Catalytic Domain Of Human Bile Salt Activated Lipase |
| PDB | 2bce_A | 0.0000001 | 120 | 259 | 65 | 231 | A Chain A, Cholesterol Esterase From Bos Taurus |
