y
Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a007826m |
Family | GT47 |
Protein Properties | Length: 395 Molecular Weight: 45991.2 Isoelectric Point: 9.0546 |
Chromosome | Chromosome/Scaffold: 89 Start: 250813 End: 253779 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 73 | 346 | 0 |
ERKLKIYAYPAPADQRYSNYQTITGKYASEGYFFKNIRESSFLTDDPELAHLFFIPISAHKLHQKVSSYDEMAAIIGEYIQRLIIKYPYWNRSLGADHFF LTCHEIDTRATERAPLLAVKNLIRVVCSPTYNSSFVPHKDVSLPLINMPFSKPPPSTANDLQNRTILGYWAGVCNTEIRERMVKLWSKDLELEIQNETAY NHARMTKFYTSKFCICPAGSRITSNRIIMAIRYGCVPVIMSDYYELPFKDVLDWRKFSVILRERDVYNLKGILK |
Full Sequence |
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Protein Sequence Length: 395 Download |
MAAALTVYPT VRAYFACSIT LSLMMIIIYN FMTYYSNKPT YTISDDYTAV AEQISGDVYH 60 WAEGFRMDYA QMERKLKIYA YPAPADQRYS NYQTITGKYA SEGYFFKNIR ESSFLTDDPE 120 LAHLFFIPIS AHKLHQKVSS YDEMAAIIGE YIQRLIIKYP YWNRSLGADH FFLTCHEIDT 180 RATERAPLLA VKNLIRVVCS PTYNSSFVPH KDVSLPLINM PFSKPPPSTA NDLQNRTILG 240 YWAGVCNTEI RERMVKLWSK DLELEIQNET AYNHARMTKF YTSKFCICPA GSRITSNRII 300 MAIRYGCVPV IMSDYYELPF KDVLDWRKFS VILRERDVYN LKGILKAKAG AEFRMLHTNL 360 LKVQNRFEWN TPPVKYDAFN MVLYDLWLRR FVIK* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-53 | 72 | 347 | 296 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI38234.1 | 0 | 72 | 394 | 1 | 325 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_195517.1 | 0 | 41 | 394 | 69 | 424 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 33 | 394 | 50 | 415 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002268836.1 | 0 | 57 | 394 | 77 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002522880.1 | 0 | 51 | 394 | 60 | 405 | catalytic, putative [Ricinus communis] |