y
Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a009039m |
Family | GT47 |
Protein Properties | Length: 356 Molecular Weight: 39955.8 Isoelectric Point: 6.5752 |
Chromosome | Chromosome/Scaffold: 15 Start: 463000 End: 464321 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 44 | 285 | 4.3e-39 |
FKIFIYTPSKPFDFPNAATASLFYTSLRRSPFLTHDPTEAHLFFVPFSPDTSTRSLSRVVRELRNDLPYWNRSLGADHFFLSPAGIDFSSDRNVLELKKN SVQISVFPVVSGYFIPHKDVTLPPLSTSTLTLLHAPVEKSTATSFLGYLRWDGETESQLVNELKSDADFFIEEKSEPPPPLNHIRGFTESKFCLFLYHGD VASMVEAMAWGCVPVVIVDRPIQDLPLMDILRWSDLALLVAT |
Full Sequence |
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Protein Sequence Length: 356 Download |
MAATTTAVFS IFFVLLPSLS AASSSPYHSA ATLFQNYHTM LTTFKIFIYT PSKPFDFPNA 60 ATASLFYTSL RRSPFLTHDP TEAHLFFVPF SPDTSTRSLS RVVRELRNDL PYWNRSLGAD 120 HFFLSPAGID FSSDRNVLEL KKNSVQISVF PVVSGYFIPH KDVTLPPLST STLTLLHAPV 180 EKSTATSFLG YLRWDGETES QLVNELKSDA DFFIEEKSEP PPPLNHIRGF TESKFCLFLY 240 HGDVASMVEA MAWGCVPVVI VDRPIQDLPL MDILRWSDLA LLVATPPHGG AAARLKQVLN 300 GLSEEKYGEM KELGVAASKH LVWNDEAQPF DAFHMVMYQL WLRRHVIRYS RSEIV* 360 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-26 | 44 | 284 | 277 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001774096.1 | 0 | 27 | 349 | 4 | 351 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002282317.1 | 0 | 1 | 355 | 1 | 360 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311191.1 | 0 | 5 | 355 | 2 | 345 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002316258.1 | 0 | 5 | 355 | 2 | 339 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002524235.1 | 0 | 1 | 355 | 3 | 337 | conserved hypothetical protein [Ricinus communis] |