Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a009452m |
Family | GT47 |
Protein Properties | Length: 342 Molecular Weight: 40354.1 Isoelectric Point: 9.9558 |
Chromosome | Chromosome/Scaffold: 275 Start: 34035 End: 35666 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 3 | 289 | 0 |
RILKVYIYQEEEKPIFHQPQLRGIYASEGWFMKLMEENRQFVTKDPQKAHLFYLPYSARQLQMALYVPNSHNMKPLSIFLRDYVNMLASKYPFWNRTHGA DHFLVACHDWGPYTLTEHEELTKNTIKALCNADVSQWIFVSGKDVSLPETIMRNPRKFLKGLGGRRVSQRPILAFFAGNNHGRVRPILIKNWSEKDRDMR IYGPLPNKVSRVMSYSQHMKSSKYCICPMGFEVNSPRIVEAIYYECVPVIIADNFIPPLNDVLNWNAFSVIVAENDIPKLKQILLAI |
Full Sequence |
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Protein Sequence Length: 342 Download |
MERILKVYIY QEEEKPIFHQ PQLRGIYASE GWFMKLMEEN RQFVTKDPQK AHLFYLPYSA 60 RQLQMALYVP NSHNMKPLSI FLRDYVNMLA SKYPFWNRTH GADHFLVACH DWGPYTLTEH 120 EELTKNTIKA LCNADVSQWI FVSGKDVSLP ETIMRNPRKF LKGLGGRRVS QRPILAFFAG 180 NNHGRVRPIL IKNWSEKDRD MRIYGPLPNK VSRVMSYSQH MKSSKYCICP MGFEVNSPRI 240 VEAIYYECVP VIIADNFIPP LNDVLNWNAF SVIVAENDIP KLKQILLAIP LRQYLIMQTN 300 IKRLKRHFLW NVRPIRYDLF HMILHSIWYS RINQIQIPHP Y* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-68 | 5 | 289 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 1 | 337 | 199 | 535 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 1 | 336 | 196 | 532 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 1 | 337 | 199 | 535 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303362.1 | 0 | 1 | 338 | 46 | 384 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530666.1 | 0 | 1 | 338 | 188 | 526 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
BX834842 | 336 | 2 | 336 | 0 |
GT051299 | 325 | 1 | 324 | 0 |
CV529785 | 252 | 43 | 293 | 0 |
EL422943 | 240 | 1 | 240 | 0 |
GO956547 | 224 | 1 | 224 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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