Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a009615m |
Family | GT47 |
Protein Properties | Length: 338 Molecular Weight: 39098.4 Isoelectric Point: 9.179 |
Chromosome | Chromosome/Scaffold: 82 Start: 627700 End: 630313 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 3 | 289 | 0 |
QMLKVYIYEDGESPIFHEPHLFGIYASEGWFMKLMEENKQFVTKDPEKAHLFYLPYSARQLQMAVYVPNSHNLRPLSVFLHGYVNMLAAKYPFWNRTHGS DHFLVACHDWGPYTLKGHNELSRNTIKVLCNADVSEGVFVAGKDVSLPETTIRNPKRPIKNLGGNRVSQRPILAFFAGNRHGRVRPVLLKHWSDKDDDMR IYGPLPNRASRLLSYPQHMKSSKYCICPMGFEVNSPRIVEAIYNECVPVIIADNFVPPLNEVLNWDEFSVVVAEKDIPNLKEILLAI |
Full Sequence |
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Protein Sequence Length: 338 Download |
MEQMLKVYIY EDGESPIFHE PHLFGIYASE GWFMKLMEEN KQFVTKDPEK AHLFYLPYSA 60 RQLQMAVYVP NSHNLRPLSV FLHGYVNMLA AKYPFWNRTH GSDHFLVACH DWGPYTLKGH 120 NELSRNTIKV LCNADVSEGV FVAGKDVSLP ETTIRNPKRP IKNLGGNRVS QRPILAFFAG 180 NRHGRVRPVL LKHWSDKDDD MRIYGPLPNR ASRLLSYPQH MKSSKYCICP MGFEVNSPRI 240 VEAIYNECVP VIIADNFVPP LNEVLNWDEF SVVVAEKDIP NLKEILLAIP LKRYIVMQTN 300 VKKLQRHFLW NAKPVPYDLF HMILHSIWSS RLNQIQI* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-68 | 5 | 289 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 1 | 337 | 199 | 535 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 1 | 336 | 196 | 532 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 1 | 337 | 199 | 535 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303362.1 | 0 | 1 | 337 | 46 | 383 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530666.1 | 0 | 1 | 337 | 188 | 525 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
BX834842 | 336 | 2 | 336 | 0 |
GO956547 | 232 | 1 | 232 | 0 |
GT051299 | 325 | 1 | 324 | 0 |
GR010292 | 218 | 121 | 338 | 0 |
GO956547 | 37 | 206 | 242 | 0.031 |
Sequence Alignments (This image is cropped. Click for full image.) |
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