Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a009659m |
Family | GT47 |
Protein Properties | Length: 336 Molecular Weight: 39191 Isoelectric Point: 6.8409 |
Chromosome | Chromosome/Scaffold: 6 Start: 632440 End: 635800 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 5 | 286 | 0 |
NMFKIYVYEEGEPPLFHDGPSKDIYSTEGIFLGLIESSKRFRTYDPNQAHVYFLPFSVVMILHHLFDPVVRDKAVLERVIGDYVRIVSTKYPYWNTSLGA DHFMLSCHDWGPRATWYEHHLYFTSMRVLCNANTSEFFNPRKDISFPEINLKVGNITGLTTTSSSNRTILAFFAGKSHGLIRPSLFQHWKDKDDDIKVFE NMPENYPLSYKEMMERSKFCLCPSGYEVASPRVVEAIYAECVPVLISEDYVLPFSDVLDWDKFTVRVSVKELGELKTILTRI |
Full Sequence |
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Protein Sequence Length: 336 Download |
MLMENMFKIY VYEEGEPPLF HDGPSKDIYS TEGIFLGLIE SSKRFRTYDP NQAHVYFLPF 60 SVVMILHHLF DPVVRDKAVL ERVIGDYVRI VSTKYPYWNT SLGADHFMLS CHDWGPRATW 120 YEHHLYFTSM RVLCNANTSE FFNPRKDISF PEINLKVGNI TGLTTTSSSN RTILAFFAGK 180 SHGLIRPSLF QHWKDKDDDI KVFENMPENY PLSYKEMMER SKFCLCPSGY EVASPRVVEA 240 IYAECVPVLI SEDYVLPFSD VLDWDKFTVR VSVKELGELK TILTRIGDDD YEALRGRVRQ 300 VQRHFVVNDP PKRYDVFHMM IHSLWLRRLN LRINA* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-68 | 7 | 286 | 300 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI28482.1 | 0 | 1 | 333 | 303 | 634 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_187419.1 | 0 | 1 | 333 | 137 | 469 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002264111.1 | 0 | 3 | 333 | 1 | 330 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002320537.1 | 0 | 1 | 332 | 62 | 392 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002524592.1 | 0 | 1 | 333 | 55 | 386 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
FD546223 | 268 | 67 | 333 | 0 |
EH682902 | 234 | 102 | 333 | 0 |
GW864815 | 307 | 19 | 323 | 0 |
GO363500 | 275 | 35 | 307 | 0 |
EG631371 | 248 | 86 | 333 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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