Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a009897m |
Family | GT47 |
Protein Properties | Length: 329 Molecular Weight: 37966.4 Isoelectric Point: 7.4995 |
Chromosome | Chromosome/Scaffold: 48 Start: 1125255 End: 1128282 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 15 | 265 | 0 |
TREAVRVTDPDSAEVFFVPFFSSLSFNVHVRNMAELNTVDEKLQLEMINILKASDYWKKSGGRDHVIPMHHPNAFRHYRDEVNASIFIVADFGRIMNISK LAKDVVAPYPHMVESYIAEEENHVDPYKSRQTLLVFRGRTKRKDEGKIRAQLHKMLNDTKDVIYEEGAASEEGFKASAEQMRSSKFCLHPAGDTPSSCRL FDAIVSHCIPVIVSDRLELPFESEIDYKEFSMFFSVNEALQPGYLIDKLRA |
Full Sequence |
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Protein Sequence Length: 329 Download |
MMASLLHEGN GSGLTREAVR VTDPDSAEVF FVPFFSSLSF NVHVRNMAEL NTVDEKLQLE 60 MINILKASDY WKKSGGRDHV IPMHHPNAFR HYRDEVNASI FIVADFGRIM NISKLAKDVV 120 APYPHMVESY IAEEENHVDP YKSRQTLLVF RGRTKRKDEG KIRAQLHKML NDTKDVIYEE 180 GAASEEGFKA SAEQMRSSKF CLHPAGDTPS SCRLFDAIVS HCIPVIVSDR LELPFESEID 240 YKEFSMFFSV NEALQPGYLI DKLRAVSEDQ WLKMWSRVKS ITHHFEFQYP PKDEDAVNMI 300 WRQVKHKVPA VKLAVHRSRR LKIPDWWR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-44 | 19 | 266 | 257 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABK24530.1 | 0 | 1 | 327 | 117 | 443 | unknown [Picea sitchensis] |
RefSeq | NP_001152546.1 | 0 | 1 | 327 | 100 | 426 | exostosin-like [Zea mays] |
RefSeq | NP_176908.2 | 0 | 1 | 327 | 103 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002456855.1 | 0 | 1 | 327 | 105 | 431 | hypothetical protein SORBIDRAFT_03g044100 [Sorghum bicolor] |
RefSeq | XP_002512333.1 | 0 | 1 | 328 | 108 | 432 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
GR071482 | 245 | 48 | 292 | 0 |
DR170144 | 269 | 8 | 273 | 0 |
CK244701 | 269 | 62 | 329 | 0 |
DT749776 | 261 | 68 | 327 | 0 |
GR071482 | 30 | 278 | 305 | 1.8 |
Sequence Alignments (This image is cropped. Click for full image.) |
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