| Basic Information | |
|---|---|
| Species | Mimulus guttatus |
| Cazyme ID | mgv1a010049m |
| Family | GH19 |
| Protein Properties | Length: 325 Molecular Weight: 35714.3 Isoelectric Point: 5.6204 |
| Chromosome | Chromosome/Scaffold: 105 Start: 19828 End: 22646 |
| Description | Chitinase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 65 | 303 | 0 |
| ISDLFQTYNFENLFPNRNSPVAHAVDFWTYRSFITAASIYEPLGFGTTGGPDMQMKEVAAFLGHVGCKTSCGYGVATGGPLAWGLCFNREMSPSQSYCDE SYKSDYPCSPGADYYGRGAIPIFWNYNYGRLADTLKLDLLNHPEYVEQNATIAFQAAIWSWMTPLKKGQPSSHDAFVGNWKPTKNDTLSNRIPGFGITMN IMYGDSVCGQGNIDAMNNIISHYQYYMDLLGLNREKAGP | |||
| Full Sequence |
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| Protein Sequence Length: 325 Download |
| METSSSRSYL KMGTAITMAV IAICGVCLVD ADSKEIIVKT VNGKKVCDQG WECKGFSEYC 60 CNQTISDLFQ TYNFENLFPN RNSPVAHAVD FWTYRSFITA ASIYEPLGFG TTGGPDMQMK 120 EVAAFLGHVG CKTSCGYGVA TGGPLAWGLC FNREMSPSQS YCDESYKSDY PCSPGADYYG 180 RGAIPIFWNY NYGRLADTLK LDLLNHPEYV EQNATIAFQA AIWSWMTPLK KGQPSSHDAF 240 VGNWKPTKND TLSNRIPGFG ITMNIMYGDS VCGQGNIDAM NNIISHYQYY MDLLGLNREK 300 AGPHEALTCG EQIVFNPSTK SSSS* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00442 | lysozyme_like | 0.0005 | 165 | 227 | 63 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| pfam00182 | Glyco_hydro_19 | 1.0e-69 | 74 | 295 | 222 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 2.0e-97 | 69 | 309 | 241 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABN08775.1 | 0 | 11 | 324 | 3 | 319 | Glycoside hydrolase, family 19 [Medicago truncatula] |
| GenBank | ACU19724.1 | 0 | 35 | 324 | 39 | 328 | unknown [Glycine max] |
| RefSeq | XP_002269474.1 | 0 | 33 | 323 | 26 | 316 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002276563.1 | 0 | 4 | 315 | 2 | 309 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002515664.1 | 0 | 7 | 318 | 2 | 313 | chitinase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3cql_B | 0 | 65 | 296 | 2 | 228 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3cql_A | 0 | 65 | 296 | 2 | 228 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 1dxj_A | 0 | 74 | 315 | 11 | 240 | A Chain A, Structure Of The Chitinase From Jack Bean |
| PDB | 3w3e_B | 0 | 74 | 315 | 12 | 241 | A Chain A, Structure Of Vigna Unguiculata Chitinase With Regulation Activity Of The Plant Cell Wall |
| PDB | 3w3e_A | 0 | 74 | 315 | 12 | 241 | A Chain A, Structure Of Vigna Unguiculata Chitinase With Regulation Activity Of The Plant Cell Wall |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| GR111570 | 245 | 1 | 245 | 0 |
| GR043249 | 242 | 1 | 242 | 0 |
| GR050188 | 242 | 1 | 242 | 0 |
| GR078300 | 241 | 1 | 241 | 0 |
| GR020213 | 240 | 1 | 240 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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