Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a010214m |
Family | GT47 |
Protein Properties | Length: 320 Molecular Weight: 35752.6 Isoelectric Point: 8.5605 |
Chromosome | Chromosome/Scaffold: 39 Start: 1407252 End: 1409970 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 83 | 247 | 4.2039e-45 |
RATLVQTFGQRNHVCLNEGSITIPPYAPPEKMQSHLIPPDTPRSIFVYFRGLFYDVNNDPEGGYYARGARASIWENFKNNPLFDISTDHPTTYYEDMQRS VFCLCPLGWAPWSPRLVEAVIFGCIPVIIADDIVLPFADAIPWEQIGVFVAEKDVPYLDTVLTSI |
Full Sequence |
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Protein Sequence Length: 320 Download |
MVFGVRALLL LLSLFLGNYG VEGIGHASVR TERISGSAGD VLEDNPVGKL KVYVYELPSK 60 YNKKILQKDP RSVKRGILPL LKRATLVQTF GQRNHVCLNE GSITIPPYAP PEKMQSHLIP 120 PDTPRSIFVY FRGLFYDVNN DPEGGYYARG ARASIWENFK NNPLFDISTD HPTTYYEDMQ 180 RSVFCLCPLG WAPWSPRLVE AVIFGCIPVI IADDIVLPFA DAIPWEQIGV FVAEKDVPYL 240 DTVLTSIPVE VILRKQRLLA NPSMKQAMLF PQPAQSGDAF HQILNGLARK LPHEGRIFLK 300 PGEKILNWTA GPIGDLKPW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-41 | 70 | 247 | 184 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC20928.1 | 0 | 53 | 319 | 75 | 341 | pectin-glucuronyltransferase [Nicotiana plumbaginifolia] |
RefSeq | NP_174064.1 | 7e-17 | 10 | 73 | 10 | 69 | GUT2; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
RefSeq | NP_174064.1 | 0 | 53 | 319 | 146 | 412 | GUT2; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
RefSeq | XP_002304637.1 | 0 | 53 | 319 | 147 | 413 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512677.1 | 0 | 68 | 319 | 2 | 253 | catalytic, putative [Ricinus communis] |