| Basic Information | |
|---|---|
| Species | Mimulus guttatus |
| Cazyme ID | mgv1a011293m |
| Family | CE1 |
| Protein Properties | Length: 287 Molecular Weight: 32250.4 Isoelectric Point: 6.6459 |
| Chromosome | Chromosome/Scaffold: 87 Start: 695017 End: 697198 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| CE1 | 27 | 283 | 0 |
| SHTLGCSMNFHIYFPPNSSPSHKFPVLYWLSGLTCTDENFIAKSGAQRVASSEGVALIVPDTSPRGLNVEGESDSWDFGVGAGFYLNATQEKWKNWRMYD YIVKELPALVHENFPQLDTTRASIFGHSMGGHGALVIYLKNLDKYKSVSAFAPIVNPTNCPWGHKAFTNYLGENKSAWEEYDATLLISKYNNLSATILID QGSDDKFLSEQLKPEIFEEACRKANVPLLLRMQAGYDHSYFTIATFIDDHIRHHAQA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 287 Download |
| MASTDKPIEI SSAKMFDGYN KRYKHYSHTL GCSMNFHIYF PPNSSPSHKF PVLYWLSGLT 60 CTDENFIAKS GAQRVASSEG VALIVPDTSP RGLNVEGESD SWDFGVGAGF YLNATQEKWK 120 NWRMYDYIVK ELPALVHENF PQLDTTRASI FGHSMGGHGA LVIYLKNLDK YKSVSAFAPI 180 VNPTNCPWGH KAFTNYLGEN KSAWEEYDAT LLISKYNNLS ATILIDQGSD DKFLSEQLKP 240 EIFEEACRKA NVPLLLRMQA GYDHSYFTIA TFIDDHIRHH AQALNL* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1506 | DAP2 | 1.0e-5 | 11 | 280 | 291 | + Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism] | ||
| pfam00756 | Esterase | 8.0e-60 | 27 | 279 | 265 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 1.0e-85 | 10 | 286 | 306 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 3.0e-138 | 10 | 284 | 276 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 0 | 6 | 286 | 281 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0018738 | S-formylglutathione hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACJ11734.1 | 0 | 6 | 286 | 4 | 284 | S-formylglutathione hydrolase [Gossypium hirsutum] |
| GenBank | ACJ84789.1 | 0 | 9 | 286 | 8 | 284 | unknown [Medicago truncatula] |
| GenBank | ACU19052.1 | 0 | 6 | 286 | 4 | 284 | unknown [Glycine max] |
| RefSeq | NP_181684.1 | 0 | 9 | 286 | 7 | 284 | SFGH (S-FORMYLGLUTATHIONE HYDROLASE); S-formylglutathione hydrolase/ hydrolase, acting on ester bonds [Arabidopsis thaliana] |
| RefSeq | XP_002284489.1 | 0 | 6 | 286 | 4 | 284 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 9 | 285 | 5 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 9 | 285 | 5 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 10 | 285 | 7 | 279 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 10 | 285 | 7 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 10 | 285 | 7 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
 | ||||
| Hit | Length | Start | End | EValue |
| DV157903 | 282 | 6 | 287 | 0 |
| GR088088 | 245 | 35 | 279 | 0 |
| DV157508 | 282 | 6 | 287 | 0 |
| JG557884 | 281 | 6 | 286 | 0 |
| GR067532 | 242 | 1 | 242 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
| Phylogeny |
|---|
 |