Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a020908m |
Family | GT47 |
Protein Properties | Length: 468 Molecular Weight: 53754.7 Isoelectric Point: 9.3894 |
Chromosome | Chromosome/Scaffold: 75 Start: 998107 End: 999599 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 77 | 391 | 0 |
LKVFMYDLPPEFHFSLLDWKSVGKSVWPDVSTEVPHYPGGLNLQHSIEYWLTMDLLNSEISKNLSGRVAKRVRNSREADVVFVPFFSSICYNRHSKLKPG QKKSTNVVLQEKLVSFLIAQKEWKRSFGKDHIVLAHHPNSLLEARMKLWPAMFVLSDFGRYPPTVANVEKDVIAPYMHVVRSYVDDSSDFGSRPTLLYFQ GSIYRKDGGRIRQELYYMLKNETDVHFSFGTVQNDGIKQATNGMRASKFCLNIAGDTPSSNRLFDAIASHCVPVIISDEIELPYEDVLDYSEFCVFVRTS DSLKEGFLLNLVRNI |
Full Sequence |
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Protein Sequence Length: 468 Download |
MVLTYKSLFC WFLMTSALLM SSWFFVLRST WLTHSVDFGF LPNSKLRYGS PLASESIIGG 60 VSSNRNPRKC DSNKPILKVF MYDLPPEFHF SLLDWKSVGK SVWPDVSTEV PHYPGGLNLQ 120 HSIEYWLTMD LLNSEISKNL SGRVAKRVRN SREADVVFVP FFSSICYNRH SKLKPGQKKS 180 TNVVLQEKLV SFLIAQKEWK RSFGKDHIVL AHHPNSLLEA RMKLWPAMFV LSDFGRYPPT 240 VANVEKDVIA PYMHVVRSYV DDSSDFGSRP TLLYFQGSIY RKDGGRIRQE LYYMLKNETD 300 VHFSFGTVQN DGIKQATNGM RASKFCLNIA GDTPSSNRLF DAIASHCVPV IISDEIELPY 360 EDVLDYSEFC VFVRTSDSLK EGFLLNLVRN IGREEWTRMW SRLKEIEHFY EFRYPSQVND 420 AVQMIWQAIF RKVPAIKRQI NKDMRFSQTG GLSESGLQSI TVPRNFG* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-52 | 77 | 391 | 325 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68950.1 | 0 | 28 | 466 | 37 | 487 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002268382.1 | 0 | 28 | 466 | 37 | 487 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002319201.1 | 0 | 2 | 447 | 14 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002325457.1 | 0 | 71 | 466 | 67 | 462 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 69 | 463 | 98 | 496 | catalytic, putative [Ricinus communis] |