Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a021350m |
Family | GT47 |
Protein Properties | Length: 486 Molecular Weight: 55911.2 Isoelectric Point: 8.7007 |
Chromosome | Chromosome/Scaffold: 17 Start: 1632748 End: 1635138 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 150 | 431 | 0 |
EKKMKVFVYEEGDPPVFHFGPCKHTYAIEGIFISNMEVSRFRTMDQDKAHLFFLPFSVTMITQVIYVKDSHEWGLMKNAASDYVNVIAQKHPYWNRSLGA DHFMLACHDWGPEISFAVPNLYKNAIRALCNANTSERFDPSRDVSIPEIHLPGGTTQGIIGGPPPSKRPILVFYAGGVHGPIRPILLEHWENKTDPDVQI YRYLPKNMSYYGMMRKSRYCICPSGYEVASPRMVEGLYLGCVPVLIKDSYVIPFSDVLNWETFAVIVPVRDIPNLKKILTGI |
Full Sequence |
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Protein Sequence Length: 486 Download |
MSSTSSLCYK HLWFLIPLLA AAVAGVVVFV GPKVSMFSSN SSYLLQDYLR TRFLNDAPLK 60 YHNSNDSTKS FTIDDGSNQK PVRNEDKYRN FTRTYSSLEM VEADLAQTRD AISQAKKGGN 120 ETRDPDPDYV PDGPMYWNPK VFHRSYLEME KKMKVFVYEE GDPPVFHFGP CKHTYAIEGI 180 FISNMEVSRF RTMDQDKAHL FFLPFSVTMI TQVIYVKDSH EWGLMKNAAS DYVNVIAQKH 240 PYWNRSLGAD HFMLACHDWG PEISFAVPNL YKNAIRALCN ANTSERFDPS RDVSIPEIHL 300 PGGTTQGIIG GPPPSKRPIL VFYAGGVHGP IRPILLEHWE NKTDPDVQIY RYLPKNMSYY 360 GMMRKSRYCI CPSGYEVASP RMVEGLYLGC VPVLIKDSYV IPFSDVLNWE TFAVIVPVRD 420 IPNLKKILTG ISSKEYMKMQ RRGVQMRRHF EINSPPKRYD VFHMILHSIW LRRLNIRLHE 480 NEYDH* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 2.0e-68 | 149 | 431 | 300 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 93 | 480 | 23 | 407 | unnamed protein product [Arabidopsis thaliana] |
RefSeq | NP_001031828.1 | 0 | 93 | 480 | 133 | 517 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002284018.1 | 0 | 149 | 481 | 1 | 333 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002524591.1 | 0 | 40 | 480 | 76 | 504 | catalytic, putative [Ricinus communis] |
RefSeq | XP_002528630.1 | 0 | 126 | 482 | 213 | 569 | catalytic, putative [Ricinus communis] |