Basic Information | |
---|---|
Species | Mimulus guttatus |
Cazyme ID | mgv1a022533m |
Family | GT47 |
Protein Properties | Length: 463 Molecular Weight: 53068.3 Isoelectric Point: 9.6299 |
Chromosome | Chromosome/Scaffold: 363 Start: 63336 End: 65269 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 87 | 386 | 0 |
KKVKIYMYDLPRRFTYGVIESYAEARGGETVGSDALLKYPGNKHSAEWYLFSDLNRPADLFYVPFFSSLSLVTNPIRPATVNVSPNRTVYNDEQTQEALM EWLEEQVYWKRNNGWDHVFICQDPNALYKIIDRVKNGVLLVSDFGRLGANQASLVKDVILPYSHRINSYKGEIGLENRKSLLFFMGNRYRKEGGKIREML FQVLENEQEVIIKHGAQSRESRRMASQGMHTSKFCLHPAGDTPSACRLFDAIVSLCVPVIVSDYIELPFEDVIDYRKIAIFLDTYTAVKPGSLVKLLRKV |
Full Sequence |
---|
Protein Sequence Length: 463 Download |
MNLRPKLRSP PLTALSIPSP PTSPLPYSSK SVLTKMPRKS LLRPTLVLAF LSLFALYSFL 60 FYNPPNYNTN TSINLDNRSF RSVDDNKKVK IYMYDLPRRF TYGVIESYAE ARGGETVGSD 120 ALLKYPGNKH SAEWYLFSDL NRPADLFYVP FFSSLSLVTN PIRPATVNVS PNRTVYNDEQ 180 TQEALMEWLE EQVYWKRNNG WDHVFICQDP NALYKIIDRV KNGVLLVSDF GRLGANQASL 240 VKDVILPYSH RINSYKGEIG LENRKSLLFF MGNRYRKEGG KIREMLFQVL ENEQEVIIKH 300 GAQSRESRRM ASQGMHTSKF CLHPAGDTPS ACRLFDAIVS LCVPVIVSDY IELPFEDVID 360 YRKIAIFLDT YTAVKPGSLV KLLRKVTLER ILEFQKELKK VKRYFEYEEA NGTVKEIWRQ 420 VSLKLPLIKL MSNRDKRIVL RDLTQPDCSC LCSNQSGVHT TL* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-67 | 86 | 386 | 321 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68074.1 | 0 | 36 | 462 | 1 | 461 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_850241.1 | 0 | 71 | 462 | 35 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002276440.1 | 0 | 10 | 462 | 16 | 494 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002322391.1 | 0 | 36 | 462 | 1 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 36 | 462 | 1 | 452 | catalytic, putative [Ricinus communis] |