| Basic Information | |
|---|---|
| Species | Mimulus guttatus |
| Cazyme ID | mgv1a023756m |
| Family | GT1 |
| Protein Properties | Length: 457 Molecular Weight: 50554.7 Isoelectric Point: 6.9918 |
| Chromosome | Chromosome/Scaffold: 2 Start: 4479194 End: 4482587 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT1 | 13 | 424 | 0 |
| VVGTRGDVQPFLAVAMRLQEHGHYVRLATHARFRDFVKSAGIDFYPLGGDPLVMVEFLVRNKHIIAAPGDRVILLEQLKAIIDSVPLACTEPDPITGEPF TAQAIIANPPAYGRVHVAEALGASLHIFSPIPGTPTNAFPHLYMQIPLSAGYWLSYIFADLMVWWGIREFVNEFRKKKLNLAPISYFNTDHVSISHLPTA YTWSPLVLPKPNDWGPLVDVVGYCFLDLGSKFIPPEDFVQWIQNGTKPIYFGFGSTLLDEPEKMMDIILEALKNTGQRGIIDRGWGDLGSTHRNIPENVF FVADYPHDWLFPQCSAVVHHGAAGTIATGLRAGCPTAVIPFCGDMFLWGKILHKKGLAPAPIPMSQLSVESLSEAITFMLQPKVKLRSMELGQLIQREDG VGAAVEAFHRHL | |||
| Full Sequence |
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| Protein Sequence Length: 457 Download |
| SSMPPKLKIA MLVVGTRGDV QPFLAVAMRL QEHGHYVRLA THARFRDFVK SAGIDFYPLG 60 GDPLVMVEFL VRNKHIIAAP GDRVILLEQL KAIIDSVPLA CTEPDPITGE PFTAQAIIAN 120 PPAYGRVHVA EALGASLHIF SPIPGTPTNA FPHLYMQIPL SAGYWLSYIF ADLMVWWGIR 180 EFVNEFRKKK LNLAPISYFN TDHVSISHLP TAYTWSPLVL PKPNDWGPLV DVVGYCFLDL 240 GSKFIPPEDF VQWIQNGTKP IYFGFGSTLL DEPEKMMDII LEALKNTGQR GIIDRGWGDL 300 GSTHRNIPEN VFFVADYPHD WLFPQCSAVV HHGAAGTIAT GLRAGCPTAV IPFCGDMFLW 360 GKILHKKGLA PAPIPMSQLS VESLSEAITF MLQPKVKLRS MELGQLIQRE DGVGAAVEAF 420 HRHLETDISS PKPSLKKVDP SNPVHWLFTQ FLIQQA* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04101 | Glyco_tran_28_C | 0.0003 | 327 | 409 | 87 | + Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site. | ||
| TIGR01426 | MGT | 6.0e-6 | 18 | 388 | 397 | + glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production [Cellular processes, Toxin production and resistance]. | ||
| pfam03033 | Glyco_transf_28 | 7.0e-22 | 9 | 152 | 144 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| COG1819 | COG1819 | 6.0e-41 | 8 | 423 | 427 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| cd03784 | GT1_Gtf_like | 8.0e-116 | 8 | 423 | 421 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABC96116.1 | 0 | 5 | 451 | 245 | 691 | sterol glucosyltransferase [Withania somnifera] |
| RefSeq | NP_175027.1 | 0 | 5 | 451 | 154 | 604 | UDP-glucose:sterol glucosyltransferase, putative [Arabidopsis thaliana] |
| RefSeq | XP_002265312.1 | 0 | 5 | 449 | 226 | 670 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002302172.1 | 0 | 5 | 450 | 156 | 606 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524293.1 | 0 | 5 | 451 | 122 | 569 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 5e-23 | 15 | 423 | 9 | 384 | A Chain A, Crystal Structure Of A Beta-Galactosidase From Bacteroides Thetaiotaomicron |
| PDB | 3h4i_A | 5e-23 | 15 | 423 | 9 | 384 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1iir_A | 2e-20 | 7 | 439 | 1 | 409 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 1rrv_B | 4e-19 | 7 | 407 | 1 | 383 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 4e-19 | 7 | 407 | 1 | 383 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| HO801427 | 414 | 37 | 448 | 0 |
| DT547914 | 323 | 25 | 346 | 0 |
| DV143911 | 274 | 118 | 391 | 0 |
| GT034671 | 346 | 80 | 424 | 0 |
| HO801427 | 54 | 7 | 60 | 0.00009 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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