| Basic Information | |
|---|---|
| Species | Mimulus guttatus |
| Cazyme ID | mgv1a023931m |
| Family | GH19 |
| Protein Properties | Length: 247 Molecular Weight: 26310.3 Isoelectric Point: 8.3343 |
| Chromosome | Chromosome/Scaffold: 14 Start: 733651 End: 735218 |
| Description | homolog of carrot EP3-3 chitinase |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 40 | 246 | 0 |
| KVSDTVTAAFFNGIANQAGGGCAGRGFYTRAAFLEAARSYPRFGGVGSADDSKREIAAFFAHVTHETGHMCHVEEINGPSKAADYCDKQNKQYPCKAGKG YYGRGPIQLSWNYNYGAAGESIGFDGLNNPEIVATDRVVSFKTALWFWMNGCHSIMTSGKGFGATIRAINGPKECGGANPSTVSARVKYYRDYCNQLRVD PGTNLRC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 247 Download |
| ACGCRANECC SQHGYCGTGE VYCGNGCRSG RCHVSSTGNK VSDTVTAAFF NGIANQAGGG 60 CAGRGFYTRA AFLEAARSYP RFGGVGSADD SKREIAAFFA HVTHETGHMC HVEEINGPSK 120 AADYCDKQNK QYPCKAGKGY YGRGPIQLSW NYNYGAAGES IGFDGLNNPE IVATDRVVSF 180 KTALWFWMNG CHSIMTSGKG FGATIRAING PKECGGANPS TVSARVKYYR DYCNQLRVDP 240 GTNLRC* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00270 | ChtBD1 | 4.0e-5 | 4 | 30 | 27 | + Chitin binding domain. | ||
| COG3179 | COG3179 | 2.0e-5 | 90 | 210 | 151 | + Predicted chitinase [General function prediction only] | ||
| cd00442 | lysozyme_like | 8.0e-9 | 127 | 208 | 82 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| pfam00182 | Glyco_hydro_19 | 2.0e-92 | 45 | 246 | 233 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 9.0e-100 | 45 | 246 | 232 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0008061 | chitin binding |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACM45716.1 | 0 | 2 | 246 | 27 | 272 | class IV chitinase [Pyrus pyrifolia] |
| GenBank | ACX94236.1 | 0 | 2 | 246 | 26 | 267 | chitinase [Lactuca sativa] |
| DDBJ | BAF44533.1 | 0 | 2 | 246 | 31 | 276 | class IV chitinase [Nicotiana tabacum] |
| RefSeq | XP_002274905.1 | 0 | 2 | 246 | 23 | 267 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002330662.1 | 0 | 2 | 246 | 33 | 275 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3hbh_A | 0 | 41 | 246 | 2 | 204 | A Chain A, Polygalacturonase From Erwinia Carotovora Ssp. Carotovora |
| PDB | 3hbe_X | 0 | 41 | 246 | 2 | 204 | A Chain A, Polygalacturonase From Erwinia Carotovora Ssp. Carotovora |
| PDB | 3hbd_A | 0 | 41 | 246 | 2 | 204 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| PDB | 3cql_B | 0 | 41 | 246 | 2 | 236 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3cql_A | 0 | 41 | 246 | 2 | 236 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EH696940 | 248 | 2 | 247 | 0 |
| EE876864 | 241 | 2 | 241 | 0 |
| ES433831 | 248 | 2 | 247 | 0 |
| DY982633 | 248 | 2 | 247 | 0 |
| DT213083 | 246 | 2 | 245 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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