Basic Information | |
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Species | Mimulus guttatus |
Cazyme ID | mgv1a025992m |
Family | GT47 |
Protein Properties | Length: 568 Molecular Weight: 66027.7 Isoelectric Point: 7.9435 |
Chromosome | Chromosome/Scaffold: 85 Start: 1108286 End: 1110082 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 137 | 477 | 0 |
SYVYVHELPSRFNHDYIKECKLLNKWHDMCQYFVNSGLGESLGNPQRLFLPSGWYITHQFSLEVIFHNRMKQYECLTNDSSKAAAIFVPYYSGLDVSRYL WDSDKASVKDSDSIELLKWLREKPEWKLMNGRDHFLVSGRITWDFRRAVDNYTEWGNKLMVLPESQNMTMLTIESSPWDKNDFAIPYPTYFHPRTDEQVL EWQNKMRRQKRRSLFCFAGAPRPNMEDSIRSEIMSQCAAAPKKCRLIECKNDKHNCLKPANVMRMFQNSVFCLQPPGDSFTRRSTFDSILAGCIPVFFSP GSAYVQYLWHLPKDHGSYSVLIPEGDVKRKGVSIDSVLSRI |
Full Sequence |
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Protein Sequence Length: 568 Download |
MENHITTRHR KKFWFAFFVL FFFWYMMLYG YDWSSIPGLS SVTHNQSDDD KNQEDSLQSM 60 GSNPIPEPRV VENNREIPIK SSDSNSVPES GSAKNQLENT STPKSDNDNV TVVSDESNNN 120 DPIVEDLPGL EKEMEPSYVY VHELPSRFNH DYIKECKLLN KWHDMCQYFV NSGLGESLGN 180 PQRLFLPSGW YITHQFSLEV IFHNRMKQYE CLTNDSSKAA AIFVPYYSGL DVSRYLWDSD 240 KASVKDSDSI ELLKWLREKP EWKLMNGRDH FLVSGRITWD FRRAVDNYTE WGNKLMVLPE 300 SQNMTMLTIE SSPWDKNDFA IPYPTYFHPR TDEQVLEWQN KMRRQKRRSL FCFAGAPRPN 360 MEDSIRSEIM SQCAAAPKKC RLIECKNDKH NCLKPANVMR MFQNSVFCLQ PPGDSFTRRS 420 TFDSILAGCI PVFFSPGSAY VQYLWHLPKD HGSYSVLIPE GDVKRKGVSI DSVLSRIPRS 480 RVSAMREKVI KLIPSVVYAD PRSRLKRLDD AFDLTVRGVV RRVEALRKEM KSGRNHSGAF 540 DSESSWKYYT FGTTAEHEWD HYFKRYR* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 2.0e-64 | 138 | 477 | 355 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN64889.1 | 0 | 53 | 546 | 236 | 710 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_180468.1 | 0 | 90 | 565 | 256 | 719 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002280815.1 | 0 | 53 | 565 | 29 | 523 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002301846.1 | 0 | 68 | 565 | 58 | 557 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |
RefSeq | XP_002313430.1 | 0 | 138 | 565 | 144 | 569 | glycosyltransferase, CAZy family GT47 [Populus trichocarpa] |