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Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna05015.1-v1.0-hybrid |
Family | GT8 |
Protein Properties | Length: 782 Molecular Weight: 87767.3 Isoelectric Point: 7.9239 |
Chromosome | Chromosome/Scaffold: 4 Start: 21809762 End: 21817497 |
Description | galactinol synthase 2 |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT8 | 79 | 324 | 0 |
AYVTFLAGNGDYVKGVVGLAKGLRKAKSAYPLIVAVLPDVPEEHLQILESQGCIVRPIEPVYPPESQTQFSMAYYVINYSKLRIWEFVEYEKLIYLDGDI QVFDNIDHLFDMPNGYFYAVMDCFCENTWSHSPQFKIGYCQQCPEKVQWPADMGSPPPRYFNAGMFVYEPGLETYHDLLETVKVTPPSSFAEQDFLNMYF KDIYQPIPPVYNLVLAMLWRHPENVDLDRVKVVHYCAAGSKPWRYT |
Full Sequence |
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Protein Sequence Length: 782 Download |
MATKKCSPRV LFHQQLVCVL HLASRRVFFH LSKSSNMADV MRTRVVIYPF WILASTMSPT 60 DLASPMSPTD LTNGVPKRAY VTFLAGNGDY VKGVVGLAKG LRKAKSAYPL IVAVLPDVPE 120 EHLQILESQG CIVRPIEPVY PPESQTQFSM AYYVINYSKL RIWEFVEYEK LIYLDGDIQV 180 FDNIDHLFDM PNGYFYAVMD CFCENTWSHS PQFKIGYCQQ CPEKVQWPAD MGSPPPRYFN 240 AGMFVYEPGL ETYHDLLETV KVTPPSSFAE QDFLNMYFKD IYQPIPPVYN LVLAMLWRHP 300 ENVDLDRVKV VHYCAAGSKP WRYTGKEEHM EREDIKMLVK KWWEIYEDPS LDYNYNDDVI 360 VKAENEPTVK LGPFIAALAD AGVDQQRSAP SDGIAPFDEI PMTLLYFWVR ILQIPPLYST 420 KPMIKDIAPM AGKYIDTDHK LFCNTKKARV FVAHDISQPF FLKKKLQLDV NVEKEIHFFY 480 ENMASICERC NLIYHVEDRC PLGKQIPKAP GLQTPSLKVT PVGGLGNLME TNFRFQGGLP 540 NPTNLPFGAG ATPSKARRPI ILKKKLFQEE ADSSAGELSL EHANVEKGTT CPSSGPAQTL 600 CLDMIREDEV ELEAESVMPT NEADSVVQTG EADSVVPTSE ADKQQGLTLA LPLAPMSLKM 660 VVKRQQPFAL TKSPVKLAAS LPSLFKSCFD DVSLKKLKMP QFTSTFTARS LNLVGARGNV 720 LIPREHATLK AAPKKKRGRP LGSKNKKPSR AQARANTSSV EDIFGSFTRS PSPSDKGKEK 780 Q* 840 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00505 | Glyco_transf_8 | 5.0e-15 | 81 | 323 | 266 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
cd04194 | GT8_A4GalT_like | 9.0e-18 | 83 | 323 | 270 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
pfam01501 | Glyco_transf_8 | 3.0e-61 | 81 | 325 | 264 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd02537 | GT8_Glycogenin | 7.0e-89 | 78 | 348 | 274 | + Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. | ||
PLN00176 | PLN00176 | 0 | 57 | 391 | 336 | + galactinol synthase |
Gene Ontology | |
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GO Term | Description |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3u2x_B | 2e-16 | 78 | 346 | 5 | 254 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
PDB | 3u2x_A | 2e-16 | 78 | 346 | 5 | 254 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
PDB | 3u2v_B | 2e-16 | 78 | 346 | 5 | 254 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
PDB | 3u2v_A | 2e-16 | 78 | 346 | 5 | 254 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
PDB | 3u2u_B | 2e-16 | 78 | 346 | 5 | 254 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
Sequence Alignments (This image is cropped. Click for full image.) |
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