Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna05162.1-v1.0-hybrid |
Family | GH19 |
Protein Properties | Length: 545 Molecular Weight: 61011.8 Isoelectric Point: 6.1915 |
Chromosome | Chromosome/Scaffold: 4 Start: 22676885 End: 22680578 |
Description | TRICHOME BIREFRINGENCE-LIKE 43 |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH19 | 353 | 520 | 0 |
GYGVATGGPLAWGLCYNKEMSPNQLYCDDYFKYTYPCAPGASYHGRGALPLYWNYNYGETGEALKVDLLNHPEYIEQNATLAFQAAIWRWMTPVKKNVPS AHDVFVGKWKPTKNDTLAKRVPGFGTTMNVLYGEQTCGQGDVDSMNNIVSHYLYYLDLIGVGREEAGP |
Full Sequence |
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Protein Sequence Length: 545 Download |
MKTTLVLLLF VVSAHQIHNT TGCDVSNGSW VYDDSYPLYN ASSCPFILKA FDCVGNGRPD 60 KDYLKYRWIP SECNLPTFNG TDLLMRFKGK SIMFVGDSLS SNQWQSLACM VYTSTSPLPK 120 YTLFRQGELS TFVFPEYNFR LLFSRNPLIV DIVNTKAGRV LKLDSISLES QQLWKGTDVV 180 IFDTWHWWLH VGRKQPWDVI QVGNQTYEDM DRLVGYEKAL NTWATWVDSN VNPAKTKVFF 240 QGVSPDHQNA SDWTLNPNSE AMNCTAESEP LLQAGSEYPR AHPAEQVAEK VLGSMSKPAR 300 LLNVTRLSEL RKDGHPSVYG LGGRRGLDCT HWCLSGVPDT WNVLLYAALT ESGYGVATGG 360 PLAWGLCYNK EMSPNQLYCD DYFKYTYPCA PGASYHGRGA LPLYWNYNYG ETGEALKVDL 420 LNHPEYIEQN ATLAFQAAIW RWMTPVKKNV PSAHDVFVGK WKPTKNDTLA KRVPGFGTTM 480 NVLYGEQTCG QGDVDSMNNI VSHYLYYLDL IGVGREEAGP HDVLNCAEQE AFERSSSSSS 540 SSSS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam14416 | PMR5N | 3.0e-24 | 21 | 74 | 54 | + PMR5 N terminal Domain. The plant family with PMR5, ESK1, TBL3 etc have a N-terminal C rich predicted sugar binding domain followed by the PC-Esterase (acyl esterase) domain. | ||
pfam00182 | Glyco_hydro_19 | 4.0e-49 | 350 | 526 | 177 | + Chitinase class I. | ||
cd00325 | chitinase_glyco_hydro_19 | 8.0e-70 | 350 | 526 | 177 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
pfam13839 | PC-Esterase | 5.0e-88 | 75 | 349 | 281 | + GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p. The PC-Esterase family is comprised of Cas1p, the Homo sapiens C7orf58, Arabidopsis thaliana PMR5 and a group of plant freezing resistance/coldacclimatization proteins typified by Arabidopsis thaliana ESKIMO1, animal FAM55D proteins, and animal FAM113 proteins. The PC-Esterase family has features that are both similar and different from the canonical GDSL/SGNH superfamily. The members of this family are predicted to have Acyl esterase activity and predicted to modify cell-surface biopolymers such as glycans and glycoproteins. The Cas1p protein has a Cas1_AcylT domain, in addition, with the opposing acyltransferase activity. The C7orf58 family has a ATP-Grasp domain fused to the PC-Esterase and is the first identified secreted tubulin-tyrosine ligase like enzyme in eukaryotes. The plant family with PMR5, ESK1, TBL3 etc have a N-terminal C rich potential sugar binding domain followed by the PC-Esterase domain. | ||
PLN02629 | PLN02629 | 3.0e-122 | 19 | 349 | 341 | + powdery mildew resistance 5 |
Gene Ontology | |
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GO Term | Description |
GO:0004568 | chitinase activity |
GO:0006032 | chitin catabolic process |
GO:0016998 | cell wall macromolecule catabolic process |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3cql_B | 6.99949e-42 | 350 | 532 | 68 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
PDB | 3cql_A | 6.99949e-42 | 350 | 532 | 68 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
PDB | 3iwr_B | 8e-40 | 350 | 537 | 124 | 303 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
PDB | 3iwr_A | 8e-40 | 350 | 537 | 124 | 303 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
PDB | 2dkv_A | 8e-40 | 350 | 537 | 124 | 303 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |