Basic Information | |
---|---|
Species | Fragaria vesca |
Cazyme ID | mrna05701.1-v1.0-hybrid |
Family | AA3 |
Protein Properties | Length: 596 Molecular Weight: 65723.3 Isoelectric Point: 9.8276 |
Chromosome | Chromosome/Scaffold: 6 Start: 28986965 End: 28989524 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
AA3 | 70 | 588 | 0 |
RQEPSYMKFVSNATDFPLEDYYDYIIVGGGTAGCPLAATLSFRFRVLLLERGGVAYGNRNLMTQEGFLASLLDVNAFDSATEAFTSEDGVPNVRGRILGG SSAINAGFYSRADQEFYKRSTFNWDLKLVNESYDWVERAIVFRPELRNWQSAFRDGLLEAGVDPYNGYSFDHVVGTKTGGSTFDTLGRRHSAADLLKYAK PLNIRVAVHATVERVLLASSTSSPVSRQSAVGVVFRDRSGRYHHAMLRKHGEVLLSAGAIGTPQLLLLSGIGPRPYLASWGIPVAYHLPYVGQFMFDNPR NGISIVPPIPLEHSLIQVVGITESGAYIESASTVIQFASPAHSGFLRTPAAPLYLTVATLMEKIVGPVSAGSLRLASTDVKVNPIVRFNYFNSPVDVQRC VNGTRKIGEILRTRSMDDFKFQGWFGNKDFRFIGPALPLDQFDFDEMADFCRRTVSTIWHYHGGCIAGKVVDRDFRVIGIDALRVVDGSTFGISPGTNPQ ATLLMLGRYVGQKIMNDRK |
Full Sequence |
---|
Protein Sequence Length: 596 Download |
MPFMIRLKPN RRESFVLSFM FLKKNREGST MAARPISLGP LLLQALAFLV LINAVAASSR 60 PPSRNPHRTR QEPSYMKFVS NATDFPLEDY YDYIIVGGGT AGCPLAATLS FRFRVLLLER 120 GGVAYGNRNL MTQEGFLASL LDVNAFDSAT EAFTSEDGVP NVRGRILGGS SAINAGFYSR 180 ADQEFYKRST FNWDLKLVNE SYDWVERAIV FRPELRNWQS AFRDGLLEAG VDPYNGYSFD 240 HVVGTKTGGS TFDTLGRRHS AADLLKYAKP LNIRVAVHAT VERVLLASST SSPVSRQSAV 300 GVVFRDRSGR YHHAMLRKHG EVLLSAGAIG TPQLLLLSGI GPRPYLASWG IPVAYHLPYV 360 GQFMFDNPRN GISIVPPIPL EHSLIQVVGI TESGAYIESA STVIQFASPA HSGFLRTPAA 420 PLYLTVATLM EKIVGPVSAG SLRLASTDVK VNPIVRFNYF NSPVDVQRCV NGTRKIGEIL 480 RTRSMDDFKF QGWFGNKDFR FIGPALPLDQ FDFDEMADFC RRTVSTIWHY HGGCIAGKVV 540 DRDFRVIGID ALRVVDGSTF GISPGTNPQA TLLMLGRYVG QKIMNDRKGG YKMVD* 600 |
Functional Domains Download unfiltered results here | ||||||
---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
TIGR03970 | Rv0697 | 9.0e-37 | 92 | 576 | 531 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. |
TIGR01810 | betA | 5.0e-42 | 92 | 576 | 556 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. |
COG2303 | BetA | 4.0e-45 | 91 | 588 | 566 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
PRK02106 | PRK02106 | 6.0e-50 | 91 | 576 | 571 | + choline dehydrogenase; Validated |
PLN02785 | PLN02785 | 0 | 70 | 589 | 557 | + Protein HOTHEAD |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 74 | 588 | 10 | 518 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
PDB | 3gdp_A | 0 | 74 | 588 | 10 | 518 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
PDB | 3gdn_B | 0 | 74 | 588 | 10 | 518 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 74 | 588 | 10 | 518 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 74 | 588 | 10 | 518 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
Sequence Alignments (This image is cropped. Click for full image.) |
---|
![]() |