Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna06060.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 502 Molecular Weight: 57352.5 Isoelectric Point: 8.9913 |
Chromosome | Chromosome/Scaffold: 4 Start: 16119653 End: 16121158 |
Description | exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 109 | 425 | 0 |
QVLKVFMYDLPTEFHFGLLDWKPKGGTVWPDLQSEVPHYPGGLNLQHSIEYWLTLDLLASELPSQPNARFAIRVLNVSEADIIFVPFFSSLSYNRFSKID PHQKKSNNKVLQDKLVQYLTAQKEWKDSGGRDHLIVAHHPNSLLDARMKLWPATFILSDFGRYPPNIANVEKDVIAPYKHVIKTFESDSSTFESRPTLLY FQGAIYRKDGGFARQELFYLLKDEKDVHFAFGTVQKNGIRNATQGMHSSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDDIELPYEDVLDYSEFCIFVR TSDAVKKGHLVNLIRSI |
Full Sequence |
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Protein Sequence Length: 502 Download |
MGERTASSLM IVTRKSLFCL FTFTSLLFVL SWVFVLRSTS RPQFIDNTLL PNSKLLAVID 60 HAISATETQN DVESSVGNRS ILVDKEEEDK STSSSRPNDG VKCDTNEKQV LKVFMYDLPT 120 EFHFGLLDWK PKGGTVWPDL QSEVPHYPGG LNLQHSIEYW LTLDLLASEL PSQPNARFAI 180 RVLNVSEADI IFVPFFSSLS YNRFSKIDPH QKKSNNKVLQ DKLVQYLTAQ KEWKDSGGRD 240 HLIVAHHPNS LLDARMKLWP ATFILSDFGR YPPNIANVEK DVIAPYKHVI KTFESDSSTF 300 ESRPTLLYFQ GAIYRKDGGF ARQELFYLLK DEKDVHFAFG TVQKNGIRNA TQGMHSSKFC 360 LNIAGDTPSS NRLFDAIASH CVPVIISDDI ELPYEDVLDY SEFCIFVRTS DAVKKGHLVN 420 LIRSIGRHEW TQMWKRLQEV QHFYEFHYPS REGDAIHMIW KAVARKVPGI RLKLHKSKRL 480 SHSPTQNKKG LTRIPSPKNF W* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-54 | 111 | 425 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |