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Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna06573.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 606 Molecular Weight: 67489.5 Isoelectric Point: 7.3987 |
Chromosome | Chromosome/Scaffold: 4 Start: 17168995 End: 17171959 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 72 | 274 | 2.2e-27 |
SCSGRYVYIHDDLPDKFGKNLLNNCKSLTQGSDKPNMCPYLENFGFGPEINNSEGVLTNKSWYSSNQFALDVIFHSKMRQYECLTSNSTLASAVYIPIYA GLEDSLHLWDPNLTARDSFGIDFLKWVSSRPEWKKMWGRDHFFAVGRIAWDFRRKTDNNTDWGSKFRFLPESKNMTMLSIEGSSWTNDIAIPYPTGFHPT KEM |
Full Sequence |
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Protein Sequence Length: 606 Download |
MAKPVAGKCA QEILFGILIS SILCFLLLFD YSTSFPGVNN GADYLYVNTK VQPTGIPKNK 60 TTVVANQSAT HSCSGRYVYI HDDLPDKFGK NLLNNCKSLT QGSDKPNMCP YLENFGFGPE 120 INNSEGVLTN KSWYSSNQFA LDVIFHSKMR QYECLTSNST LASAVYIPIY AGLEDSLHLW 180 DPNLTARDSF GIDFLKWVSS RPEWKKMWGR DHFFAVGRIA WDFRRKTDNN TDWGSKFRFL 240 PESKNMTMLS IEGSSWTNDI AIPYPTGFHP TKEMPSFKCL QVTRLQFRWE QLCASGYNNE 300 SVTKISLLLA AYREFLYRRS AFDSFLAGCI PVFFHPGSAY NQYLWHLPKN HTKYSMFIPV 360 KNVTDLNEVS IEKTLLGISK TKELAMREEL IRLIPNLVYS DPMSRLETPD AFDIAVKRIL 420 ERIENVRKMS KEGKDPSFGF TDEEGNHVAD ALANYGTPST GFVWWDTTPK VVASNRNEDR 480 YALLKFRVRP CGFSGEASSS FLFDAAKGTY GFFGEGSYSL CSFSGTAESM DGARRSLGFI 540 PAASPAKLLL PFSGEASSSF LFDAAEGPCG FSGEGSYSLC GFSGTAESMD GTTTLSFCKR 600 PGGSP* 660 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-32 | 72 | 378 | 356 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |