| Basic Information | |
|---|---|
| Species | Fragaria vesca |
| Cazyme ID | mrna09449.1-v1.0-hybrid |
| Family | GT28 |
| Protein Properties | Length: 857 Molecular Weight: 93406 Isoelectric Point: 6.2904 |
| Chromosome | Chromosome/Scaffold: 5 Start: 10400215 End: 10406352 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT28 | 249 | 407 | 0 |
| LLVLGGSLGANAINIALLNLYYQMLLEKEDLFIIWQTGVEAYNEMESLVKNHPRLLLKPFMHKMDLAYAAADLVVSRAGAMTCYEILATGKPSILIPSPD ADEGHQFKNASLMADLAGARVITEDELDSTTLGNAIEEIVGDESKMADMSERALKAANV | |||
| Full Sequence |
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| Protein Sequence Length: 857 Download |
| MAAFSHLSFT PSPPPTKLGT LNFKVTSCLS LKQSNDQTLA SQNDAVLFDS LRVVFAAGGT 60 GGHIYPAVAI ADELKTTNPN AQILFFGIPK SMESKAIPNA GHDFAAVPAA KLHRPVLSPR 120 NVFLPYHLIK SIIWSYYKLR EFDPHIVIGT GGYVSFPVGI AAALRGVKLV IQEQNAVPGI 180 ANWLLSFLAE VVFVAFNSTI DCFPSASGKK CVVCGNPVRL SLRKNVSKEA ARGRFFPKCG 240 KEVEDVKVLL VLGGSLGANA INIALLNLYY QMLLEKEDLF IIWQTGVEAY NEMESLVKNH 300 PRLLLKPFMH KMDLAYAAAD LVVSRAGAMT CYEILATGKP SILIPSPDAD EGHQFKNASL 360 MADLAGARVI TEDELDSTTL GNAIEEIVGD ESKMADMSER ALKAANVNAS EEIAHHVARL 420 LELLPLRSSL LERDIIKNLS FILLTKGLMR NLVARKAESD KQPESGSSSS LPSCSKHGSD 480 LRSLTTAFGT DRPYFTPIRN SDPRPEPLRV SARRTPTPSA GVSLDLTKKN DPRWSVCTAD 540 ELHYVSVPNS DWNLALWRYL PSPQTTEPRN HPLLLLSGLA TNAIGYDLSP ESSFARSMSS 600 QGYDTWILEV RGAGLSTHGT ELGEINGLLE AGQNRATVVS GLSQTPLNIM EVGQRAVTSF 660 ADFQERFSTG LEDFQKQLGK LDWDFDHYLE EDVPVAADPA QVLNVPVPFG AIYTALHHLV 720 SRTPALSWLK PQVSAQDMMD PELYEKLVLN NFCTVPAKLL LQLATAFEEG GLCDRSGTFF 780 YKEHLCKSNV PILALGGDQD LICPPEAVYE TVKVIPEHLV TFKVLGELGG PHYAHYDLVG 840 GRGGLNSSFS NFLPYC* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04101 | Glyco_tran_28_C | 3.0e-29 | 258 | 413 | 157 | + Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site. | ||
| COG0707 | MurG | 1.0e-74 | 52 | 414 | 364 | + UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] | ||
| TIGR01133 | murG | 4.0e-80 | 52 | 414 | 364 | + undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]. | ||
| PRK00726 | murG | 1.0e-102 | 52 | 417 | 372 | + undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional | ||
| cd03785 | GT1_MurG | 7.0e-117 | 52 | 414 | 364 | + MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030246 | carbohydrate binding |
| GO:0030259 | lipid glycosylation |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3s2u_A | 9.80909e-45 | 53 | 422 | 5 | 359 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_B | 2e-36 | 52 | 424 | 8 | 357 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_A | 2e-36 | 52 | 424 | 8 | 357 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1f0k_B | 2e-36 | 52 | 424 | 8 | 357 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| PDB | 1f0k_A | 2e-36 | 52 | 424 | 8 | 357 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| Hydropathy |
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| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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