Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna11048.1-v1.0-hybrid |
Family | GT24 |
Protein Properties | Length: 1613 Molecular Weight: 181555 Isoelectric Point: 5.7727 |
Chromosome | Chromosome/Scaffold: 5 Start: 20646017 End: 20666405 |
Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT24 | 1310 | 1554 | 0 |
INIFSIASGHLYERFLKIMILSVLKNTRRPVKFWFIKNYLSPQFKDVIPRMADEYGFEYQLITYKWPTWLHKQKEKQRIIWAYKILFLDVIFPLSLEKVI FVDADQIIRADMGELYDMDIKGRPLAYTPFCDNNKDMDGYRFWRQVLTDKGLFPFFILLAVMDCPISNISIVFTCALYVVDLKKFRETAAGDNLRDLPNY AQHTVPIFSLPQEWLWCESWCGNATKSKAKTIDLCNNPMTKEPKL |
Full Sequence |
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Protein Sequence Length: 1613 Download |
MGTRLAYAFI ILICLIGSVS AQNRRPKNVQ VAVRAKWSAT PLLLEAGELL SREHKDNFWE 60 FIDIWHHSDK DDLDSYNAKG CLKTILKHGR SILSEPLASL FEFSLTLRSA SPRLVLYRQL 120 AEESLSSFPL VDETNSRSTS GNSETNEHVE IRKSDHLDVG LNPKSPNGKC CWVDTGGALF 180 FDAAELKSWL HSPKDCSRDS FQQPELFEFD HIHFDSTVGS PVAVLYGALG TGCFREFHVT 240 LVEAAKEGHV KYVVRPVLPS GCEAEIDRCG AVGAKDSLNL GGYGVELALK NMEYKAMDDS 300 TIKKGVTLED PRTEDLSQEV RGFIFSKFLK FGGGSILDRF NGERTIFETV RGKERRPELT 360 SEIMAFRDYL LSSIISDTLD VWELKDLGHQ TAQRIVQATD PLQAMQEINQ NFPTVVSSLS 420 RMKLNDSVKD EITANQRMIP PGKSLMAMNG ALINIEDVDL YLLVDLVHQD LLLADHFSKL 480 KIPHSTARKL LSTLPPPESN MFRVDFRSNH VHYLNNLEED AMYKRWRSNL NEVGLLSVSI 540 LMPVFPGQLR YIRKNLFHAV SVIDPSTSID MLISLYENNF PMRFGVVLYS SKLIKHIETS 600 SDDSQIEEDI STSIKKLRGE SDGSADDLEM HHVEGAFVET VLPKVKSPPQ GILLKLEREQ 660 TYKERAHEST IFVFKLGLAK LQCCLLMNGL VLDSNEEALT NSMNDEMPRI QEQVYYGHIN 720 SQTDVLNKFL SESGTTRYNP QIIAGGKPRF TSLCTSVLGG EGVFNDISYL HSPETVDDLK 780 PVTHLLVVDV SSKKGMKLIH EALQYLIEGS DRARVGVLFS VNQGADLSTL LFVEVFQITA 840 SLHRCVCSFF EQNHMLAPSE GAEITQAFID KVSELAEKNG LSSKAYKSAL SDFSAEELRK 900 RLNKVAQFLY RQLGLDSGVN GVITNGRVTV VNEESSLLSH DLSLLESVEF TQRIKHIVEI 960 IEEVKWQDVD PDTLTSKFIS DTIMFVSSSM AMRDRSSEGA RFEVLNADYS AIVLNNENSS 1020 IHIDAVIDPL SPSGQKLSSI LRVLWKYVQP SMRIVLNPLS SLVDLPLKNY YRYVVPTVDD 1080 FSTTDYTVNG PKAFFANMPL SKTLTMNLDV PDPWLVEPVI AVHDLDNILL ENLGETRTLQ 1140 AVFELEALVL TGHCSEKDHD PPRGLQLIIG TKSAPHLVDT LVMANLGYWQ MKVSPGVWYL 1200 QLAPGRSSEL YVLKDEGDGS QSKTLSKRIT INDLRGTVVH LEVVKKKGKE HEKLLLSDVN 1260 EKTQDATEGN SWNSNFIKWA SGLIGGSEHS KQSENTSWEK GKGGRHGKTI NIFSIASGHL 1320 YERFLKIMIL SVLKNTRRPV KFWFIKNYLS PQFKDVIPRM ADEYGFEYQL ITYKWPTWLH 1380 KQKEKQRIIW AYKILFLDVI FPLSLEKVIF VDADQIIRAD MGELYDMDIK GRPLAYTPFC 1440 DNNKDMDGYR FWRQVLTDKG LFPFFILLAV MDCPISNISI VFTCALYVVD LKKFRETAAG 1500 DNLRDLPNYA QHTVPIFSLP QEWLWCESWC GNATKSKAKT IDLCNNPMTK EPKLQGARRI 1560 VSEWPDLDLE ARQFTAKILG DEVAIQEPPP DPNQPGSVMD SPPEDLESKA EL* 1620 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01501 | Glyco_transf_8 | 2.0e-5 | 1314 | 1435 | 128 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd04194 | GT8_A4GalT_like | 2.0e-11 | 1310 | 1435 | 128 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
cd00505 | Glyco_transf_8 | 1.0e-46 | 1310 | 1554 | 269 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
pfam06427 | UDP-g_GGTase | 1.0e-78 | 980 | 1185 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
cd06432 | GT8_HUGT1_C_like | 8.0e-140 | 1310 | 1554 | 265 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. |
Gene Ontology | |
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GO Term | Description |
GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
GO:0006486 | protein glycosylation |