Basic Information | |
---|---|
Species | Fragaria vesca |
Cazyme ID | mrna13072.1-v1.0-hybrid |
Family | GH19 |
Protein Properties | Length: 629 Molecular Weight: 67001.1 Isoelectric Point: 6.6556 |
Chromosome | Chromosome/Scaffold: 1 Start: 7315682 End: 7320253 |
Description | basic chitinase |
View CDS |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GH19 | 74 | 133 | 2.2e-23 |
ALEHRNDGRCKSNGFYKYDAFITAARSFNGFGTTGDVATRKKEIAAFLGQTSHETTGQRM | |||
GH19 | 191 | 299 | 0 |
FNYNYAQVGQAIGVDLINNPDLVATDPVVSFKTAVWFWMTPQGNKPSSHDVIIGRWNPSSADRAAGRVPGYGVITNIVNGALECGRGADARVADRIGFYK RYCDIFGLA | |||
GH19 | 384 | 618 | 0 |
VAGIITSSLFDEMLKHRNDPQCKGNGFYSYDAFITAAGSFPAFGTTGDDVTKKKELAAFLAQTSHETTGGSGWAGAPDGPYAWGYCFVNEITQDVRCTSP EYPCAPGKKYYGRGPIQLTHNYNYAQAGAAIKEDLINNPDLVATDPVVAFKTAIWFWMTPQSNKPSSHDVITGRWNPSAADISAGRVPGYGVITNIINGG IECGHGPDDKVVDRIGFYRRYSDILGVSPGDNLDC |
Full Sequence |
---|
Protein Sequence Length: 629 Download |
MSLAKISFPS EKGMYGIYPA THFEKCGSIQ GHRHSNVGSK PEGQRVQIGS VAANLGIVAT 60 QANTVELVAK ANVALEHRND GRCKSNGFYK YDAFITAARS FNGFGTTGDV ATRKKEIAAF 120 LGQTSHETTG QRMEDGQLHQ MARMLGDIAL SGNSTRLTIA LHQPSIHALP TENITAEDLF 180 NLLSESCFPI FNYNYAQVGQ AIGVDLINNP DLVATDPVVS FKTAVWFWMT PQGNKPSSHD 240 VIIGRWNPSS ADRAAGRVPG YGVITNIVNG ALECGRGADA RVADRIGFYK RYCDIFGLAS 300 VNMKLHTFII VSFTLLLGIS AEQCGRQAGG ATCPNGLCCS EYGWCGTTPD YCATGCQSQC 360 TPSGGGGSPT TPSSPTPSGG GSDVAGIITS SLFDEMLKHR NDPQCKGNGF YSYDAFITAA 420 GSFPAFGTTG DDVTKKKELA AFLAQTSHET TGGSGWAGAP DGPYAWGYCF VNEITQDVRC 480 TSPEYPCAPG KKYYGRGPIQ LTHNYNYAQA GAAIKEDLIN NPDLVATDPV VAFKTAIWFW 540 MTPQSNKPSS HDVITGRWNP SAADISAGRV PGYGVITNII NGGIECGHGP DDKVVDRIGF 600 YRRYSDILGV SPGDNLDCNN QVPFAPNA* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd06921 | ChtBD1_GH19_hevein | 3.0e-19 | 322 | 360 | 39 | + Hevein or Type 1 chitin binding domain subfamily co-occuring with family 19 glycosyl hydrolases or with barwin domains. This subfamily includes Hevein, a major IgE-binding allergen in natural rubber latex. ChtBD1 is a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements. | ||
cd00325 | chitinase_glyco_hydro_19 | 1.0e-89 | 75 | 297 | 237 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
pfam00182 | Glyco_hydro_19 | 3.0e-90 | 75 | 299 | 233 | + Chitinase class I. | ||
cd00325 | chitinase_glyco_hydro_19 | 6.0e-140 | 388 | 618 | 232 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
pfam00182 | Glyco_hydro_19 | 6.0e-143 | 387 | 618 | 234 | + Chitinase class I. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0004568 | chitinase activity |
GO:0006032 | chitin catabolic process |
GO:0008061 | chitin binding |
GO:0016998 | cell wall macromolecule catabolic process |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3iwr_B | 0 | 322 | 624 | 2 | 298 | A Chain A, Structure Of Ugt78g1 Complexed With Myricetin And Udp |
PDB | 3iwr_B | 0 | 75 | 300 | 71 | 286 | A Chain A, Structure Of Ugt78g1 Complexed With Myricetin And Udp |
PDB | 3iwr_A | 0 | 322 | 624 | 2 | 298 | A Chain A, Structure Of Ugt78g1 Complexed With Myricetin And Udp |
PDB | 3iwr_A | 0 | 75 | 300 | 71 | 286 | A Chain A, Structure Of Ugt78g1 Complexed With Myricetin And Udp |
PDB | 2dkv_A | 0 | 322 | 624 | 2 | 298 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |
Sequence Alignments (This image is cropped. Click for full image.) |
---|