| Basic Information | |
|---|---|
| Species | Fragaria vesca |
| Cazyme ID | mrna13147.1-v1.0-hybrid |
| Family | GH18 |
| Protein Properties | Length: 300 Molecular Weight: 31610.6 Isoelectric Point: 7.7453 |
| Chromosome | Chromosome/Scaffold: 7 Start: 21128888 End: 21129787 |
| Description | chitinase A |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH18 | 27 | 247 | 6.3e-32 |
| IAIYWGQNGNEGTLAQTCASGNYKFVNIAFLSSFGNGRTPALNLAGHCDPYTKGSCTKFSSQIKSCQAKGIKVILSIGGGAEAYSLTSSEDARQVGVYLW NNFLGGQSSSRPLGDAVLDGVDFDIEGGNDQYYDDLARYLSAQSKKGSKKVYLTAAPQCPFPDAYIGNALKTGLFDYVWVQFYNNPPCQYTSGDVTSLED SWKQWTSAIPAQKIFLGLPAA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 300 Download |
| MASISAAALL SLATLLLLGV GSNAGGIAIY WGQNGNEGTL AQTCASGNYK FVNIAFLSSF 60 GNGRTPALNL AGHCDPYTKG SCTKFSSQIK SCQAKGIKVI LSIGGGAEAY SLTSSEDARQ 120 VGVYLWNNFL GGQSSSRPLG DAVLDGVDFD IEGGNDQYYD DLARYLSAQS KKGSKKVYLT 180 AAPQCPFPDA YIGNALKTGL FDYVWVQFYN NPPCQYTSGD VTSLEDSWKQ WTSAIPAQKI 240 FLGLPAAPQA AGSGFIPAAA LTSKVLPGIK TSAKYGGVML WSKYYDDLDG YSSSIKNHV* 300 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00598 | GH18_chitinase-like | 3.0e-8 | 27 | 210 | 196 | + The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods. Chitinases have been identified in viruses, bacteria, fungi, protozoan parasites, insects, and plants. The structure of the GH18 domain is an eight-stranded beta/alpha barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel. The GH18 family includes chitotriosidase, chitobiase, hevamine, zymocin-alpha, narbonin, SI-CLP (stabilin-1 interacting chitinase-like protein), IDGF (imaginal disc growth factor), CFLE (cortical fragment-lytic enzyme) spore hydrolase, the type III and type V plant chitinases, the endo-beta-N-acetylglucosaminidases, and the chitolectins. The GH85 (glycosyl hydrolase, family 85) ENGases (endo-beta-N-acetylglucosaminidases) are closely related to the GH18 chitinases and are included in this alignment model. | ||
| COG3469 | COG3469 | 7.0e-13 | 48 | 287 | 271 | + Chitinase [Carbohydrate transport and metabolism] | ||
| cd02871 | GH18_chitinase_D-like | 1.0e-15 | 49 | 294 | 293 | + GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus. | ||
| pfam00704 | Glyco_hydro_18 | 1.0e-32 | 25 | 246 | 243 | + Glycosyl hydrolases family 18. | ||
| cd02877 | GH18_hevamine_XipI_class_III | 4.0e-135 | 25 | 297 | 280 | + This conserved domain family includes xylanase inhibitor Xip-I, and the class III plant chitinases such as hevamine, concanavalin B, and PPL2, all of which have a glycosyl hydrolase family 18 (GH18) domain. Hevamine is a class III endochitinase that hydrolyzes the linear polysaccharide chains of chitin and peptidoglycan and is important for defense against pathogenic bacteria and fungi. PPL2 (Parkia platycephala lectin 2) is a class III chitinase from Parkia platycephala seeds that hydrolyzes beta(1-4) glycosidic bonds linking 2-acetoamido-2-deoxy-beta-D-glucopyranose units in chitin. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2hvm_A | 0 | 25 | 299 | 1 | 273 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
| PDB | 1llo_A | 0 | 25 | 299 | 1 | 273 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
| PDB | 1hvq_A | 0 | 25 | 299 | 1 | 273 | A Chain A, Crystal Structures Of Hevamine, A Plant Defence Protein With Chitinase And Lysozyme Activity, And Its Complex With An Inhibitor |
| PDB | 1kr0_A | 0 | 25 | 299 | 1 | 273 | A Chain A, Hevamine Mutant D125aY183F IN COMPLEX WITH TETRA-Nag |
| PDB | 1kr1_A | 0 | 25 | 299 | 1 | 273 | A Chain A, Hevamine Mutant D125aE127A IN COMPLEX WITH TETRA-Nag |
