| Basic Information | |
|---|---|
| Species | Fragaria vesca |
| Cazyme ID | mrna13375.1-v1.0-hybrid |
| Family | GH29 |
| Protein Properties | Length: 488 Molecular Weight: 55368.6 Isoelectric Point: 6.7602 |
| Chromosome | Chromosome/Scaffold: 7 Start: 22271922 End: 22273728 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH29 | 42 | 339 | 0 |
| QLKWQQREIIMFLHFGVNTFTGLERGTGNENPAIFNPVALDASQWVSVAEDAGISLMILTAKHHDGFCLWPSKYTDHTVKKSPWKNGHGDVVQELVDASK PRGVDVGLYLSPWDRHDHRYGMEKPYNEYYLAQLQELLTRYGSLREIWFDGFKGEDAPNMSYFFTDWFSMVKELQSSINIFSDAGPDVRWVGNEDGFAGE SCWSTINRTSLSIGNASIEHYLNRGDPKGTDWLPAESDVSIRKGWFWHSSESPKKLSQLLKIYYNSVGRNSVLLLNVPPNSTGLISEVDVERLREFRT | |||
| Full Sequence |
|---|
| Protein Sequence Length: 488 Download |
| MGKQWCSLFI ITFFELCTFT FSRLEQVTPP PLPILPLPTY HQLKWQQREI IMFLHFGVNT 60 FTGLERGTGN ENPAIFNPVA LDASQWVSVA EDAGISLMIL TAKHHDGFCL WPSKYTDHTV 120 KKSPWKNGHG DVVQELVDAS KPRGVDVGLY LSPWDRHDHR YGMEKPYNEY YLAQLQELLT 180 RYGSLREIWF DGFKGEDAPN MSYFFTDWFS MVKELQSSIN IFSDAGPDVR WVGNEDGFAG 240 ESCWSTINRT SLSIGNASIE HYLNRGDPKG TDWLPAESDV SIRKGWFWHS SESPKKLSQL 300 LKIYYNSVGR NSVLLLNVPP NSTGLISEVD VERLREFRTA IDTIFSTNVA EKCSIKVSSQ 360 RGGIGGGFGP ENVLDSDHLW TYWAPRDGDK DDHWIEFRAD EGMRFNAIRI QEAIGLGQRI 420 KRHKICVDGK VVANGTTVGY KRLHRLNNGV VHGQTVRIRI EESRGNLPLI SSIGLHFDPY 480 WHPEKGV* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 2.0e-32 | 76 | 337 | 278 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 2.0e-34 | 76 | 337 | 280 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 1.0e-51 | 42 | 475 | 452 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 33 | 476 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 33 | 476 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3ues_B | 0 | 38 | 471 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 38 | 471 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 38 | 471 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
