y
Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna13376.1-v1.0-hybrid |
Family | GH29 |
Protein Properties | Length: 489 Molecular Weight: 54871.9 Isoelectric Point: 6.871 |
Chromosome | Chromosome/Scaffold: 7 Start: 22274623 End: 22276515 |
Description | alpha-L-fucosidase 1 |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH29 | 41 | 339 | 0 |
SQLKWQQRELIMFLHFGVNTFTDSEWGTGHESPAIFNPAGLDANQWVKTASDAGISLVVLTAKHHDGFCLWPSKYTEHSVGSSPWRSGHGDVVQELVNAA TTHGGIDIGLYLSPWDRHDRRYGHEVAYNQYYLAQLQELLSRYGSVREIWFDGSKGPNAPNMSYYFADWFSMVKELQSTINIFSDAGPDVRWVGNEQGFA GSTSWSTINRSSLSIGNASIEGYLNTGDPQGMDWLPPECDVSIRNGWFWHKSESPKKLSTLLEIYYNSVGRNCVLLLNVPPNSTGLISQADVQRLRELR |
Full Sequence |
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Protein Sequence Length: 489 Download |
MAKQWRSLCI FTFLQLSTFT ISRLEQVPTP PLPILPLPTY SQLKWQQREL IMFLHFGVNT 60 FTDSEWGTGH ESPAIFNPAG LDANQWVKTA SDAGISLVVL TAKHHDGFCL WPSKYTEHSV 120 GSSPWRSGHG DVVQELVNAA TTHGGIDIGL YLSPWDRHDR RYGHEVAYNQ YYLAQLQELL 180 SRYGSVREIW FDGSKGPNAP NMSYYFADWF SMVKELQSTI NIFSDAGPDV RWVGNEQGFA 240 GSTSWSTINR SSLSIGNASI EGYLNTGDPQ GMDWLPPECD VSIRNGWFWH KSESPKKLST 300 LLEIYYNSVG RNCVLLLNVP PNSTGLISQA DVQRLRELRG AIDTIFSSNL AENCSIKVSS 360 QRGGKGGGFG PENVLDSDHL WTYWAPKDGD KEEHWIEFRG RDETKGLRFN VIRIQEAIGL 420 GQRIKKHEIY VDGKMVANGT TVGYKRLHRL EGGVLHGQIV RIKLEDSKGL PLISSIGLHF 480 DPYWHPSV* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01120 | Alpha_L_fucos | 1.0e-28 | 76 | 338 | 283 | + Alpha-L-fucosidase. | ||
smart00812 | Alpha_L_fucos | 2.0e-30 | 45 | 338 | 339 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
COG3669 | COG3669 | 9.0e-60 | 42 | 478 | 452 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] |
Gene Ontology | |
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GO Term | Description |
GO:0004560 | alpha-L-fucosidase activity |
GO:0005975 | carbohydrate metabolic process |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3eyp_B | 0 | 33 | 479 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
PDB | 3eyp_A | 0 | 33 | 479 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
PDB | 3ues_B | 0 | 38 | 474 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
PDB | 3ues_A | 0 | 38 | 474 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
PDB | 3mo4_B | 0 | 38 | 474 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |