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Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna13394.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 487 Molecular Weight: 56043.6 Isoelectric Point: 7.6282 |
Chromosome | Chromosome/Scaffold: 7 Start: 22368187 End: 22369647 |
Description | glycosyltransferase 18 |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 85 | 427 | 0 |
CSSGRVFVYDLPKSLNLEILQNCDNLNPWSSRCDALANDGFGQPATGIAGVVPESLAPAWYWTDQFVTEVIFHNRIMHHKCRVHDPENATAFYIPFYVGL AVGKYLWSNSSTAQDRDFHCETMLSWLQTQPYYRRSDGWDHFLTMGRISWDFRRSRDPDWGSSCIYKPGMRNITRLLIERNPWDYFDVGVPYPTGFHPRT DADVTDWQSFVRSRNRSKLFCFAGAKRSLIRNDFRGVLLSQCQSEPESCRVVDCGGSRCSNGTSLILETFLDSDFCLQPRGDSFTRRSIFDCMVAGSIPV FFWKRTAYFQYEWFLPGEPESYSVFIDRNSVKNGTASIKNVLA |
Full Sequence |
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Protein Sequence Length: 487 Download |
MLSIPAQPSP ELQQKRPKSP DPLNLLTSLK QLIHHPRTWL LMAILSLQVI LLFTLTTRSF 60 SSRQDLSPPY TPLSGSTTPQ PEPECSSGRV FVYDLPKSLN LEILQNCDNL NPWSSRCDAL 120 ANDGFGQPAT GIAGVVPESL APAWYWTDQF VTEVIFHNRI MHHKCRVHDP ENATAFYIPF 180 YVGLAVGKYL WSNSSTAQDR DFHCETMLSW LQTQPYYRRS DGWDHFLTMG RISWDFRRSR 240 DPDWGSSCIY KPGMRNITRL LIERNPWDYF DVGVPYPTGF HPRTDADVTD WQSFVRSRNR 300 SKLFCFAGAK RSLIRNDFRG VLLSQCQSEP ESCRVVDCGG SRCSNGTSLI LETFLDSDFC 360 LQPRGDSFTR RSIFDCMVAG SIPVFFWKRT AYFQYEWFLP GEPESYSVFI DRNSVKNGTA 420 SIKNVLAGYS REEVRKMREK VIDYIPNFLY AKPQEGLETV KDAFDIALER VLRRFEEHGE 480 WGFKWQ* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-53 | 85 | 429 | 360 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Sequence Alignments (This image is cropped. Click for full image.) |
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