Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna15204.1-v1.0-hybrid |
Family | AA7 |
Protein Properties | Length: 442 Molecular Weight: 48628.5 Isoelectric Point: 6.3825 |
Chromosome | Chromosome/Scaffold: 2 Start: 22559683 End: 22563090 |
Description | cytokinin oxidase/dehydrogenase 1 |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA7 | 54 | 240 | 3.2e-24 |
MSRAEPLAVMHPASAEDVARLVRAAYSSAKGFSVSARGHGHSINGQAQARNGVVIAMSGGNRAGGRRETAAGVVSEKGLYVDAWGGELWIEVLRATLEHG LAPKSWTDYLYLSVGGTLSNAGISGQAFNHGPQISNVLELDVVTGKGELLTCSEERNAELFHAVLGGLGQFGIITRARIALEPAPTR |
Full Sequence |
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Protein Sequence Length: 442 Download |
MAMKLVLVIF AICRLLVTVG LTMDPAELLR LVVDGQLSLD PSDVETASKD FGLMSRAEPL 60 AVMHPASAED VARLVRAAYS SAKGFSVSAR GHGHSINGQA QARNGVVIAM SGGNRAGGRR 120 ETAAGVVSEK GLYVDAWGGE LWIEVLRATL EHGLAPKSWT DYLYLSVGGT LSNAGISGQA 180 FNHGPQISNV LELDVVTGKG ELLTCSEERN AELFHAVLGG LGQFGIITRA RIALEPAPTR 240 EIEALLKELD FVPTSVFTTD LPYVDFLDRV HKAELKLRSK GLWDVPHPWL NLFVPKSRIS 300 DFDEGVFKGI LGNKTSGPVL IYPMNKDKWD QRSSVVTPDE DVFYLVALLR SALDSGDETH 360 TLEYLTNQNR RIFKFCDEAG IKVKQYLPHY TTQQEWMDHF GDKWPLFYQR KMEFDPRRIL 420 ATGQRIFTGP SSVSTAGHDQ L* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam01565 | FAD_binding_4 | 5.0e-27 | 59 | 206 | 149 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. |
COG0277 | GlcD | 8.0e-28 | 27 | 424 | 466 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] |
pfam09265 | Cytokin-bind | 3.0e-110 | 240 | 427 | 189 | + Cytokinin dehydrogenase 1, FAD and cytokinin binding. Members of this family adopt an alpha+beta sandwich structure with an antiparallel beta-sheet, in a ferredoxin-like fold. They are predominantly found in plant cytokinin dehydrogenase 1, where they are capable of binding both FAD and cytokinin substrates. The substrate displays a 'plug-into-socket' binding mode that seals the catalytic site and precisely positions the carbon atom undergoing oxidation in close contact with the reactive locus of the flavin. |
PLN02441 | PLN02441 | 6.0e-125 | 241 | 432 | 192 | + cytokinin dehydrogenase |
PLN02441 | PLN02441 | 1.0e-144 | 1 | 240 | 242 | + cytokinin dehydrogenase |
Gene Ontology | |
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GO Term | Description |
GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
GO:0009690 | cytokinin metabolic process |
GO:0016491 | oxidoreductase activity |
GO:0019139 | cytokinin dehydrogenase activity |
GO:0050660 | flavin adenine dinucleotide binding |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3s1d_A | 0 | 25 | 260 | 17 | 247 | A Chain A, Glu381ser Mutant Of Maize Cytokinin OxidaseDEHYDROGENASE COMPLEXED With N6-Isopentenyladenosine |
PDB | 3s1d_A | 0 | 240 | 428 | 330 | 516 | A Chain A, Glu381ser Mutant Of Maize Cytokinin OxidaseDEHYDROGENASE COMPLEXED With N6-Isopentenyladenosine |
PDB | 3kjm_A | 0 | 25 | 260 | 17 | 247 | A Chain A, Glu381ser Mutant Of Maize Cytokinin OxidaseDEHYDROGENASE COMPLEXED With N6-Isopentenyladenosine |
PDB | 3kjm_A | 0 | 240 | 428 | 330 | 516 | A Chain A, Glu381ser Mutant Of Maize Cytokinin OxidaseDEHYDROGENASE COMPLEXED With N6-Isopentenyladenosine |
PDB | 2qpm_A | 0 | 25 | 260 | 17 | 247 | A Chain A, Leu492ala Mutant Of Maize Cytokinin OxidaseDEHYDROGENASE COMPLEXED With Benzylurea Inhibitor Cpbu |