Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna16325.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 294 Molecular Weight: 33086.4 Isoelectric Point: 7.177 |
Chromosome | Chromosome/Scaffold: 1 Start: 18684037 End: 18685268 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 38 | 179 | 1.5e-28 |
LSVYVYTLPPRFNVDFLDRCRTIAATYTLCPSVANSGLGQPLFDDTPGKVTSWFNTMQFASELIFHARLLNHPCRTWDPTRASLFYVPFYGGLYYLNQFK ESNSTARNQLAVDLANYIQAQPMWKRTIGKDHFMRNLSPART |
Full Sequence |
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Protein Sequence Length: 294 Download |
MSYTIINNIN IPQHLTTDTG STTDEEPFLL STCVDPSLSV YVYTLPPRFN VDFLDRCRTI 60 AATYTLCPSV ANSGLGQPLF DDTPGKVTSW FNTMQFASEL IFHARLLNHP CRTWDPTRAS 120 LFYVPFYGGL YYLNQFKESN STARNQLAVD LANYIQAQPM WKRTIGKDHF MRNLSPARTN 180 NVGRNGNMAR QGEGNGEASH LFSFVDKSAY NQYAWFLPED ASAYSVLIDE KSNASKKIEE 240 ELLKISSDRV QRMREKLIDL IRSLTYAHPI ASNLGFEDVA VASLAKHVKN TIN* 300 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-22 | 36 | 185 | 150 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Sequence Alignments (This image is cropped. Click for full image.) |
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