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Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna16326.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 486 Molecular Weight: 55414.9 Isoelectric Point: 9.514 |
Chromosome | Chromosome/Scaffold: 1 Start: 18686725 End: 18688182 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 95 | 421 | 0 |
QQVSVYVYTLPAKFNLGLLHNCHDLNFRTDMCPHVANSGLGQPLATIGSTLETNNSNSWYATNQFAAEMIFHARLLNHPCRTYDPARATLFYVPYYGGLH VSSKFRERNQTARDELDVGLVDYLQFQPTWQKQKGKDHFMALGRVVRDFKSSWVGAGRLLKLAGVENMSVLIIERNPFNGSNQHGIPYPSYFHPSTWHDM STWQTKMRETHRRHLFSFIGAKRRKAAIRNKFIKQCGESTRCMLLNCRGGNDEARKCQEPSEVLKVMSESVFCLQAPGDTFTRRSTFDSVLAGCIPVFFS PHTAYSQYQWYLPEERSEYSVYIDQRS |
Full Sequence |
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Protein Sequence Length: 486 Download |
MFSGEKKPPI LLRFSSSLLL FLSAAFLIFW FPSSPDTLIQ QKHDHDHIQH HDSPHVNQNR 60 NQNNNNSNSN SSSSKNDDVL TAPTKPYVTV PKCNQQVSVY VYTLPAKFNL GLLHNCHDLN 120 FRTDMCPHVA NSGLGQPLAT IGSTLETNNS NSWYATNQFA AEMIFHARLL NHPCRTYDPA 180 RATLFYVPYY GGLHVSSKFR ERNQTARDEL DVGLVDYLQF QPTWQKQKGK DHFMALGRVV 240 RDFKSSWVGA GRLLKLAGVE NMSVLIIERN PFNGSNQHGI PYPSYFHPST WHDMSTWQTK 300 MRETHRRHLF SFIGAKRRKA AIRNKFIKQC GESTRCMLLN CRGGNDEARK CQEPSEVLKV 360 MSESVFCLQA PGDTFTRRST FDSVLAGCIP VFFSPHTAYS QYQWYLPEER SEYSVYIDQR 420 SKARKRIEDE LLKIPSEKVK RMREKIIGLI PSLTYANPNA SDFGFEDAVD VALASLAKKV 480 KKFVD* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-53 | 99 | 436 | 352 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |