Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna17328.1-v1.0-hybrid |
Family | GT13 |
Protein Properties | Length: 489 Molecular Weight: 55825.1 Isoelectric Point: 7.2332 |
Chromosome | Chromosome/Scaffold: 2 Start: 10117795 End: 10123291 |
Description | alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, putative |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT13 | 66 | 480 | 0 |
IQIRLFATQSQYADRLADAIESENQCTSQLRSLIDQISLQQGQIETMKDSIVEQKEQLEQECGQLKALVQELERKDVERLTNKEQAPVAAVVIMACNRAD YLERTIKSILKYQSSVATKFPLFVSQDGSHPGVKDKALSYDQLTYMQLHGYIPVCLGHYKWALDGLFYKHKFNRVIILEDDMEIAPDFFDYFEAAADLLD KDKSIMAVSSWNDNGQKQFVYDPEVLYRSDFFPGLGWMLSRSTWDELSPKWPKAYPCYKRITKVDNFFVQKCAEHITLGNMYAFLPSLSHLTSQGSSLGQ FYKQYLEPIKLNDVPVDWKSMDLSYLMEDKYIKHFAEIVKKAKPVHGADLVLKARNIAVDVRIPYNNQPDFERIANEFGIFEEWKDGIPRTAYKGVVVFR HQNRQRIFLVGPGSL |
Full Sequence |
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Protein Sequence Length: 489 Download |
MKKTGVLLAK QSTRIAAGSV PDSNPTRLAQ LVGLNSPRSE LPNVMKNFLC DFRFLLLLAA 60 AAFIYIQIRL FATQSQYADR LADAIESENQ CTSQLRSLID QISLQQGQIE TMKDSIVEQK 120 EQLEQECGQL KALVQELERK DVERLTNKEQ APVAAVVIMA CNRADYLERT IKSILKYQSS 180 VATKFPLFVS QDGSHPGVKD KALSYDQLTY MQLHGYIPVC LGHYKWALDG LFYKHKFNRV 240 IILEDDMEIA PDFFDYFEAA ADLLDKDKSI MAVSSWNDNG QKQFVYDPEV LYRSDFFPGL 300 GWMLSRSTWD ELSPKWPKAY PCYKRITKVD NFFVQKCAEH ITLGNMYAFL PSLSHLTSQG 360 SSLGQFYKQY LEPIKLNDVP VDWKSMDLSY LMEDKYIKHF AEIVKKAKPV HGADLVLKAR 420 NIAVDVRIPY NNQPDFERIA NEFGIFEEWK DGIPRTAYKG VVVFRHQNRQ RIFLVGPGSL 480 KQLGIDDS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG4942 | COG4942 | 0.008 | 65 | 150 | 86 | + Membrane-bound metallopeptidase [Cell division and chromosome partitioning] | ||
cd00761 | Glyco_tranf_GTA_type | 2.0e-8 | 156 | 303 | 148 | + Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities. | ||
cd02514 | GT13_GLCNAC-TI | 1.0e-128 | 153 | 477 | 351 | + GT13_GLCNAC-TI is involved in an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides. Alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (GLCNAC-T I , GNT-I) transfers N-acetyl-D-glucosamine from UDP to high-mannose glycoprotein N-oligosaccharide, an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides. The enzyme is an integral membrane protein localized to the Golgi apparatus. The catalytic domain is located at the C-terminus. These proteins are members of the glycosy transferase family 13. | ||
pfam03071 | GNT-I | 1.0e-179 | 63 | 487 | 446 | + GNT-I family. Alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (GNT-I, GLCNAC-T I) EC:2.4.1.101 transfers N-acetyl-D-glucosamine from UDP to high-mannose glycoprotein N-oligosaccharide. This is an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides. The enzyme is an integral membrane protein localised to the Golgi apparatus, and is probably distributed in all tissues. The catalytic domain is located at the C-terminus. |
Gene Ontology | |
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GO Term | Description |
GO:0000139 | Golgi membrane |
GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity |
GO:0006487 | protein N-linked glycosylation |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1foa_A | 0 | 149 | 477 | 4 | 337 | A Chain A, Crystal Structure Of N-acetylglucosaminyltransferase I |
PDB | 1fo9_A | 0 | 149 | 477 | 4 | 337 | A Chain A, Crystal Structure Of N-acetylglucosaminyltransferase I |
PDB | 2apc_A | 0 | 153 | 477 | 2 | 331 | A Chain A, Crystal Structure Of N-acetylglucosaminyltransferase I |
PDB | 2am5_A | 0 | 153 | 477 | 2 | 331 | A Chain A, Crystal Structure Of N-acetylglucosaminyltransferase I |
PDB | 2am4_A | 0 | 153 | 477 | 2 | 331 | A Chain A, Crystal Structure Of N-acetylglucosaminyltransferase I |