| Basic Information | |
|---|---|
| Species | Fragaria vesca |
| Cazyme ID | mrna19212.1-v1.0-hybrid |
| Family | GH18 |
| Protein Properties | Length: 424 Molecular Weight: 48156.9 Isoelectric Point: 9.4554 |
| Chromosome | Chromosome/Scaffold: 7 Start: 2013772 End: 2017272 |
| Description | Glycosyl hydrolase superfamily protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH18 | 98 | 415 | 2.4e-36 |
| YPVLAYITPWNSKGYDLAKRFNSKFTHISPVWYDLKSQGASLILEGRHNADIGWISDLRRAGDAWVLPRVVLEAFPAELLAKKKQRKKAIDLIVSECKEM GYDGIVLESWSRWAVYRVLNDPKMRNLALQFIKDLGDALHAVTSERNNKNRLQLVYVIGPPHSETLQVNDFGPKDLQSLSDAVDGFSLMTYDFSGPHNPG PNAPLKWIESILQLLLGTNKNTALANKILLGINFYGNDFILSEGQGGGAITGRDYLSLLEKHKPDFRWEKNSAEHLLLYTDDDHNNHAVFYPSLLSISMR LEEARKWGCGISIWEIGQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 424 Download |
| MAKKKDRRVV APSSDRRKDR VEPPHQLARS TSFSNRNLAI TFFVVFVVSS AVSVLVYRRL 60 SFAPITDRTE SYVFRRGLVK PDENAHVSEN ATGRHYKYPV LAYITPWNSK GYDLAKRFNS 120 KFTHISPVWY DLKSQGASLI LEGRHNADIG WISDLRRAGD AWVLPRVVLE AFPAELLAKK 180 KQRKKAIDLI VSECKEMGYD GIVLESWSRW AVYRVLNDPK MRNLALQFIK DLGDALHAVT 240 SERNNKNRLQ LVYVIGPPHS ETLQVNDFGP KDLQSLSDAV DGFSLMTYDF SGPHNPGPNA 300 PLKWIESILQ LLLGTNKNTA LANKILLGIN FYGNDFILSE GQGGGAITGR DYLSLLEKHK 360 PDFRWEKNSA EHLLLYTDDD HNNHAVFYPS LLSISMRLEE ARKWGCGISI WEIGQGLDYF 420 YDLL 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00704 | Glyco_hydro_18 | 9.0e-14 | 174 | 415 | 257 | + Glycosyl hydrolases family 18. | ||
| COG3858 | COG3858 | 5.0e-21 | 176 | 424 | 257 | + Predicted glycosyl hydrolase [General function prediction only] | ||
| cd02874 | GH18_CFLE_spore_hydrolase | 7.0e-29 | 100 | 424 | 341 | + Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis. | ||
| smart00636 | Glyco_18 | 1.0e-32 | 100 | 415 | 354 | + Glyco_18 domain. | ||
| cd02876 | GH18_SI-CLP | 6.0e-152 | 96 | 424 | 334 | + Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome. SI-CLP has a glycosyl hydrolase family 18 (GH18) domain but lacks a chitin-binding domain. The catalytic amino acids of the GH18 domain are not conserved in SI-CLP, similar to the chitolectins YKL-39, YKL-40, and YM1/2. Human SI-CLP is sorted to late endosomes and secretory lysosomes in alternatively activated macrophages. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3bxw_A | 0 | 76 | 424 | 48 | 393 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
| PDB | 3bxw_B | 0 | 76 | 424 | 48 | 393 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
| PDB | 3cz8_B | 0.00002 | 212 | 413 | 86 | 308 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |
| PDB | 3cz8_A | 0.00002 | 212 | 413 | 86 | 308 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |
| PDB | 1ll7_B | 0.0005 | 178 | 343 | 107 | 269 | A Chain A, Structure Of The E171q Mutant Of C. Immitis Chitinase 1 |
