Basic Information | |
---|---|
Species | Fragaria vesca |
Cazyme ID | mrna20131.1-v1.0-hybrid |
Family | AA7 |
Protein Properties | Length: 535 Molecular Weight: 59864.1 Isoelectric Point: 9.4358 |
Chromosome | Chromosome/Scaffold: 3 Start: 8295293 End: 8296897 |
Description | FAD-binding Berberine family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
AA7 | 69 | 529 | 0 |
NLRFNESYTRKPYLIITALHVSHVQQVILCAQKHNLQMKIRSGGHDYEGVSYVAEVPFFILDLFNLRTINVDIKTETAWVQAGATLGEVYYRIHEKSKVH GFPAGVCPTVGVGGLFSGGGYGVMLRKYGLSVDNIVDAQIVDVHGRLLDRKSMGEDLFWAITGGGGASFGVVIAYKINLVPVPETVTVFKVIRTLEQNAT DIVYHWQYVAHKLDNDLFIRLTMDVVNVTGSQTGEKTLRATFMALFLGDSARLLSVMNKSFPELGLKQSDCQEMSWVESTLFWTSFPNGTALDALLRRDP QVLTHLKRKSDYVKQPIPKAGLKWIIQKMIELQTPMLTFNPYGGRMAEIAASAKPFPHRAGNLWKVQYATNWNASGSEAAEKYIDLTRKLFKYMTPFVSK NPREAFFNYKDLDIGINHNDKGSYFEGRVYGVKYFKENFDKLVLIKTKVDPGNFFRNEQSI |
Full Sequence |
---|
Protein Sequence Length: 535 Download |
MAIRRLSQLL LPILLVLSVS CIASASSSAP DNFVSCLLSH SLPSHPIGPA IYTPNNASYS 60 SVLESYIRNL RFNESYTRKP YLIITALHVS HVQQVILCAQ KHNLQMKIRS GGHDYEGVSY 120 VAEVPFFILD LFNLRTINVD IKTETAWVQA GATLGEVYYR IHEKSKVHGF PAGVCPTVGV 180 GGLFSGGGYG VMLRKYGLSV DNIVDAQIVD VHGRLLDRKS MGEDLFWAIT GGGGASFGVV 240 IAYKINLVPV PETVTVFKVI RTLEQNATDI VYHWQYVAHK LDNDLFIRLT MDVVNVTGSQ 300 TGEKTLRATF MALFLGDSAR LLSVMNKSFP ELGLKQSDCQ EMSWVESTLF WTSFPNGTAL 360 DALLRRDPQV LTHLKRKSDY VKQPIPKAGL KWIIQKMIEL QTPMLTFNPY GGRMAEIAAS 420 AKPFPHRAGN LWKVQYATNW NASGSEAAEK YIDLTRKLFK YMTPFVSKNP REAFFNYKDL 480 DIGINHNDKG SYFEGRVYGV KYFKENFDKL VLIKTKVDPG NFFRNEQSIP TLPY* 540 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG0277 | GlcD | 2.0e-12 | 92 | 532 | 464 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
pfam08031 | BBE | 7.0e-15 | 473 | 530 | 58 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
pfam01565 | FAD_binding_4 | 6.0e-16 | 80 | 217 | 139 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
GO:0016491 | oxidoreductase activity |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3vte_A | 0 | 31 | 533 | 5 | 514 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
PDB | 4dns_B | 0 | 32 | 532 | 12 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 4dns_A | 0 | 32 | 532 | 12 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsj_B | 0 | 28 | 532 | 6 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsj_A | 0 | 28 | 532 | 6 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |