| Basic Information | |
|---|---|
| Species | Fragaria vesca |
| Cazyme ID | mrna20178.1-v1.0-hybrid |
| Family | AA7 |
| Protein Properties | Length: 544 Molecular Weight: 61021.9 Isoelectric Point: 8.7561 |
| Chromosome | Chromosome/Scaffold: 3 Start: 8531520 End: 8533151 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 79 | 294 | 0 |
| APKPEFIFTPTHDSHVQTAVICSKQLGIHLRVRSGGHDYEGLSYVSEIETPFIVLDLAKLRSVNVDIQQNSAWIQAGATIGEVYYRIAEQSATHGFPAGL CTSLGVGGHITGGAYGSMMRKYGLGVDNAVDAQIVDVDGRILDRETMGEDLFWAIRGGGGASFGIILWWKIKLVPVPSTVTVFTVARTLEQDGTKLLHRW QQVAATELDEDLFIRV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 544 Download |
| MVLPNCSKFL LFPFLLLLSS SSSLAHSPSS SEDVFSQCLS YHSKVSISFS STIFTPNNSA 60 FTTILQSTAE NLRYVVPSAP KPEFIFTPTH DSHVQTAVIC SKQLGIHLRV RSGGHDYEGL 120 SYVSEIETPF IVLDLAKLRS VNVDIQQNSA WIQAGATIGE VYYRIAEQSA THGFPAGLCT 180 SLGVGGHITG GAYGSMMRKY GLGVDNAVDA QIVDVDGRIL DRETMGEDLF WAIRGGGGAS 240 FGIILWWKIK LVPVPSTVTV FTVARTLEQD GTKLLHRWQQ VAATELDEDL FIRVIIQLTS 300 DSKSGKRTVT TLYQAQFLGG VERLLYVMQT GFPELGLTRK DCTETSWIKS VMYIANYPNG 360 TQPEILLQGK STTRSYFKAK SDFVKDPIPE TGLEGLRKRL MEETNPVLIW TPYGGMMSKI 420 SESDTPFPHR KGVLFKIQYL TIWQAANQDE AKHMDWIRKL YNYMAPYVTM FPRQAYVNYR 480 DLDLGINKKS NLSFIEASSW GYRYFKDNFN RLIKIKTKVD PYNFFRHEQS ITPLPLTVGR 540 TMN* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam08031 | BBE | 1.0e-17 | 475 | 531 | 57 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. |
| COG0277 | GlcD | 1.0e-19 | 82 | 251 | 181 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] |
| pfam01565 | FAD_binding_4 | 1.0e-25 | 82 | 221 | 141 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 29 | 535 | 1 | 514 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 53 | 534 | 26 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 53 | 534 | 26 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_B | 0 | 28 | 534 | 5 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_A | 0 | 28 | 534 | 5 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
