| Basic Information | |
|---|---|
| Species | Fragaria vesca |
| Cazyme ID | mrna20856.1-v1.0-hybrid |
| Family | GT47 |
| Protein Properties | Length: 350 Molecular Weight: 39617.4 Isoelectric Point: 8.8772 |
| Chromosome | Chromosome/Scaffold: 7 Start: 16785229 End: 16786278 |
| Description | Exostosin family protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 66 | 292 | 1.4e-33 |
| HVQSLFYTSLLDSDLATNVSDHAHLFFLPFPPDLPTRSLARLIRTIRTDYPYWNRTLGADHFYLSCSGVGYESDRNLVELKKNSIQISCFPTSPGQLIPH KDITLPPLASSHAPTVNTTTFLGYIRSNWVNDSAIVDELRVNPEFLIESEISKPKIHAQRLSSSKFCIFEYGAGDVSGIGEALTFGCVPVVITDRPIQDL PFMDVLRWQEMALFVGRSGGAKELERV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 350 Download |
| MSTTTATATI FLLLLLHTTH SKPLPIPHLT SPYLNPSTFS ANYDSMVKNF RIFIYKPTPP 60 FTYPNHVQSL FYTSLLDSDL ATNVSDHAHL FFLPFPPDLP TRSLARLIRT IRTDYPYWNR 120 TLGADHFYLS CSGVGYESDR NLVELKKNSI QISCFPTSPG QLIPHKDITL PPLASSHAPT 180 VNTTTFLGYI RSNWVNDSAI VDELRVNPEF LIESEISKPK IHAQRLSSSK FCIFEYGAGD 240 VSGIGEALTF GCVPVVITDR PIQDLPFMDV LRWQEMALFV GRSGGAKELE RVLVRACWER 300 HDQMRRLGAE AGKHLAWNAP PRAKDAFHTL VYQLWLRRHT IRYARRETA* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 7.0e-20 | 46 | 280 | 283 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
