| Basic Information | |
|---|---|
| Species | Fragaria vesca |
| Cazyme ID | mrna21972.1-v1.0-hybrid |
| Family | CE1 |
| Protein Properties | Length: 315 Molecular Weight: 35113 Isoelectric Point: 7.5453 |
| Chromosome | Chromosome/Scaffold: 6 Start: 10845449 End: 10850725 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE1 | 51 | 306 | 0 |
| STILGCSMTFHIYFPPSPSPSHKFPVLYWLSGLTCTDENFIIKSGAQRAAAKEGIALIAPDTSPRGLSIEGEAESWDFGVGAGFYLNATQEKWKNWRMYD YVVKELPKLLNENFPQLDTLRASISGHSMGGHGALTIYLRNLDKYKSVSAFSPIANPTNCPWGQKAFSNYLGGNKTDWEEYDATCLVKKVKDVSATILID QGEDDKFLNDQLLPHKFAEACSSAKVPLLLRSQPGYDHSYYFISTFIDDHISHHAQ | |||
| Full Sequence |
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| Protein Sequence Length: 315 Download |
| MPNLEGVGCV FYIRKVPAIK SSSAKMEECK PTEISSSKMF EGYNKRYKHF STILGCSMTF 60 HIYFPPSPSP SHKFPVLYWL SGLTCTDENF IIKSGAQRAA AKEGIALIAP DTSPRGLSIE 120 GEAESWDFGV GAGFYLNATQ EKWKNWRMYD YVVKELPKLL NENFPQLDTL RASISGHSMG 180 GHGALTIYLR NLDKYKSVSA FSPIANPTNC PWGQKAFSNY LGGNKTDWEE YDATCLVKKV 240 KDVSATILID QGEDDKFLND QLLPHKFAEA CSSAKVPLLL RSQPGYDHSY YFISTFIDDH 300 ISHHAQAVKL PPQP* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00756 | Esterase | 2.0e-55 | 51 | 301 | 263 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 4.0e-83 | 34 | 312 | 308 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 1.0e-131 | 34 | 308 | 276 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 0 | 28 | 310 | 283 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0006508 | proteolysis |
| GO:0008236 | serine-type peptidase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0018738 | S-formylglutathione hydrolase activity |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 33 | 306 | 5 | 278 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 33 | 306 | 5 | 278 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 34 | 305 | 7 | 275 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 34 | 305 | 7 | 275 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 34 | 305 | 7 | 275 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Hydropathy |
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| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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