Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna24260.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 448 Molecular Weight: 51789.6 Isoelectric Point: 8.6802 |
Chromosome | Chromosome/Scaffold: 6 Start: 30407482 End: 30409168 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 119 | 398 | 0 |
LFRTFVYEEGEPPIFHNGPCKNIYSMEGLFLSFMETDTKFRTSDPEEAHVYFLPFSVVMIIEYLFHPVIRDKAVLQRTVVDYVRVISNKYPFWNRSLGAD HVMLSCHDWGPRATWYVRQLYFVAIRVLCNANTSEHFNPKKDASFPEINLVTGEITGLIGGLPPSKRSVLAFFAGRMHGRIRPLLFQHWKEKDENLLVYE KLPKNASYQDMLKQSKYCICPSGHEVASPRIVEAIYAECVPVLISQHYVLPFSDVLDWESFSIQVSVSEIPQLKEILMRI |
Full Sequence |
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Protein Sequence Length: 448 Download |
MAFFAIVSLV VTPKSYKGRS SWFGVTSTRG VSSESQLRFN NISGHTGFTS KSVLKRDNEK 60 GDVNLERIEA GLATARELIR EATTLNQTSP LEDADYVPNG DIYRNAYAFH RSYLLMESLF 120 RTFVYEEGEP PIFHNGPCKN IYSMEGLFLS FMETDTKFRT SDPEEAHVYF LPFSVVMIIE 180 YLFHPVIRDK AVLQRTVVDY VRVISNKYPF WNRSLGADHV MLSCHDWGPR ATWYVRQLYF 240 VAIRVLCNAN TSEHFNPKKD ASFPEINLVT GEITGLIGGL PPSKRSVLAF FAGRMHGRIR 300 PLLFQHWKEK DENLLVYEKL PKNASYQDML KQSKYCICPS GHEVASPRIV EAIYAECVPV 360 LISQHYVLPF SDVLDWESFS IQVSVSEIPQ LKEILMRIPE EKYRRMQERV KQVQMHFVVN 420 NPPKRYDVFH MIIHSIWLRR LNVRIYS* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 3.0e-63 | 116 | 398 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Sequence Alignments (This image is cropped. Click for full image.) |
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