Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna24860.1-v1.0-hybrid |
Family | GT20 |
Protein Properties | Length: 1001 Molecular Weight: 111857 Isoelectric Point: 6.6241 |
Chromosome | Chromosome/Scaffold: 3 Start: 3997937 End: 4006173 |
Description | trehalose-6-phosphate synthase |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 87 | 409 | 0 |
KQRLLVVANRLPVSAVRKGEDSWQLEISVGGLVSALLGVKEFDARWIGWAGVNVPDTVGQKALTKALAEKRCIPVFLDEEIVHQYYNGYCNNILWPLFHY LGLPQEDRLATTRSFQSQFDAYKKANQMFADVVNKHYEDGDVVWCHDYHLMFLPKCLKEHNSRMKVGWFLHTPFPSSEIHRTLPSRSELLRSVLAADLVG FHTYDYARHFVSACTRILGLEGTPEGVEDQGKLTRVAAFPIGIDSDRFIRALELPQVQEHMKELKERFAGRKVMLGVDRLDMIKGIPQKILAFEKFLEEN LSWRDKVVLLQIAVPTRTDVPEC | |||
GT20 | 440 | 585 | 0 |
DQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHALCALYAVTDVALVTSLRDGMNLVSYEFVACQASKKGVLILSEFAGAAQSLGAGAILVNPWNI TEVAASIGYALNMPADEREKRHHHNFMHVTTHTSQEWAATFVSELN |
Full Sequence |
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Protein Sequence Length: 1001 Download |
MPGNKYNCNP LTPRSRLERL LRERELRRSN LASQTNEDGN RHAELSSFFL TDGENSALSG 60 DEDSADGAAA ARAFVDGCEW QEGRPSKQRL LVVANRLPVS AVRKGEDSWQ LEISVGGLVS 120 ALLGVKEFDA RWIGWAGVNV PDTVGQKALT KALAEKRCIP VFLDEEIVHQ YYNGYCNNIL 180 WPLFHYLGLP QEDRLATTRS FQSQFDAYKK ANQMFADVVN KHYEDGDVVW CHDYHLMFLP 240 KCLKEHNSRM KVGWFLHTPF PSSEIHRTLP SRSELLRSVL AADLVGFHTY DYARHFVSAC 300 TRILGLEGTP EGVEDQGKLT RVAAFPIGID SDRFIRALEL PQVQEHMKEL KERFAGRKVM 360 LGVDRLDMIK GIPQKILAFE KFLEENLSWR DKVVLLQIAV PTRTDVPECR IEKSFHLAYS 420 TPEVLPESNI FLRNAVSLTD QKLTSQVHEI VGRINGRFGT LTAVPIHHLD RSLDFHALCA 480 LYAVTDVALV TSLRDGMNLV SYEFVACQAS KKGVLILSEF AGAAQSLGAG AILVNPWNIT 540 EVAASIGYAL NMPADEREKR HHHNFMHVTT HTSQEWAATF VSELNDTIVE AQLRTRQVPP 600 LLPIKGSVDR YFQSNNRLLI LGFNATLTEP KDTLGRRGGQ IREMELKLHP DLKEPLKKLC 660 DDSKTTIVVV SGSDRSVLDY NFGDYNMWLA AENGMFLRLT TGEWMTTMPE NLNMDWVDSV 720 KHVFEYFTER TPRSHFELRE TSLVWNYKYA DVEFGRLQAR DLLQHLWTGP ISNASVDVVQ 780 GGRSVEVRAV GVTKGAAIDR ILGEIVHNKG MKAPIDYVLC IGHFLPKDED LYTFFEPELP 840 SEAPAQSIPR PTSVPTPVNP SLPKISTGKS GSKGSRLKKQ RSLSTLEKRA NIGIVNAWRP 900 TLMRDRMSLH EGSSVLDLKG DNYFSCAVGR KRSSARYLLK SSDDVVTLLK ELAEGGEPVP 960 VDSVDGAMPL DREGGALPLD SEGGAVPHNS EAGEQSTENI * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 2.0e-10 | 913 | 953 | 41 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03064 | PLN03064 | 0 | 1 | 960 | 969 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 80 | 847 | 768 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
TIGR02400 | trehalose_OtsA | 0 | 89 | 586 | 500 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
pfam00982 | Glyco_transf_20 | 0 | 88 | 586 | 505 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 0 | 89 | 596 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 0 | 89 | 596 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 0 | 89 | 596 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 0 | 89 | 596 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1uqu_B | 0 | 89 | 596 | 3 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
Sequence Alignments (This image is cropped. Click for full image.) |
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