Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna26011.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 491 Molecular Weight: 55983.7 Isoelectric Point: 9.6877 |
Chromosome | Chromosome/Scaffold: 5 Start: 7107654 End: 7109534 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 116 | 429 | 0 |
LLRVFMYDLPPEFHFGLLGWKEMENQTWPQHIPPYPGGLNLQHSIEYWLTLDILSSDNVNVVRPCTLVRVHNPREADFIFVPFFASLSYNRHSKLHEKEK VSVNKRLQDKLVQFLMGRNEWKRKGGKDHLIVAHHPNSMLDARKKLGSAMFVLADFGRYPAEIANLGKDIIAPYRHLVKTVPSSKSATFKERPILVYFRG AIYRKDGGVIRQELYYLLKDEKDVDFNFGSIGGNGVRKATQGMASSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDEIEVPFEDVLDYSQFCIFVRGDD AIKKGYLLKLLRGI |
Full Sequence |
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Protein Sequence Length: 491 Download |
MSEKSRIPSK FISSLITVSG FLLILSSVFL LQSGNTSFIP RSVFELMLVN GTSVYFEPHA 60 EKEPIKCSFL SSEVPQVDAI QPLKRMSESA CQVSNPSKKV GSVGRKNMVC DSKQALLRVF 120 MYDLPPEFHF GLLGWKEMEN QTWPQHIPPY PGGLNLQHSI EYWLTLDILS SDNVNVVRPC 180 TLVRVHNPRE ADFIFVPFFA SLSYNRHSKL HEKEKVSVNK RLQDKLVQFL MGRNEWKRKG 240 GKDHLIVAHH PNSMLDARKK LGSAMFVLAD FGRYPAEIAN LGKDIIAPYR HLVKTVPSSK 300 SATFKERPIL VYFRGAIYRK DGGVIRQELY YLLKDEKDVD FNFGSIGGNG VRKATQGMAS 360 SKFCLNIAGD TPSSNRLFDA IASHCVPVII SDEIEVPFED VLDYSQFCIF VRGDDAIKKG 420 YLLKLLRGIN EEKWTKMWER LKEVVHHFEY QYPSLPGDAV DMIWQAVSRK ISSVQFKYNR 480 KRRYDRSQLV * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-55 | 117 | 429 | 322 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |