Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna26479.1-v1.0-hybrid |
Family | GT1 |
Protein Properties | Length: 1208 Molecular Weight: 132228 Isoelectric Point: 6.331 |
Chromosome | Chromosome/Scaffold: 7 Start: 15446094 End: 15453554 |
Description | Eukaryotic aspartyl protease family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT1 | 999 | 1183 | 2.3e-37 |
CDLFDKSGDDYLQWLDTKADSSVVYVSFGSMVVLRSGQMEEMLHGLVDSGLPVLWVIRKSGNEGDQETENLINNTLKKEQGLIVPWCSQVEVLSHKSVGC CVSHCGWNSTIESLAAGVPVVGCPHFADQTTNAKLVEELWGSGVRARANEEGVIERAEIKRCLEVVMGDGVRGEEMRRNAQKWKS |
Full Sequence |
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Protein Sequence Length: 1208 Download |
MPPLLLHLLL LHFFTYNSRL CFSSPQPKTL ILPLKTQTLP KPSNKLSFHH NVTLTISLTV 60 GLPPQNVTMV LDTGSELSWL HCKKTPILTN VFNPLASKSY IPVSCSTPTC RTRTRDLSIP 120 VSCDPKKLCH ATLSYADASS LEGNLASDTF FLGSSGQPGT VFGCMDSGFS SNSEEDAKTT 180 GLLGMNRGSL SFITQMGYPK FSYCISGRDA SGVLLFGQAS FPWLGPLNYT PLVQMSNPLP 240 YFDRVAYTVQ LEGIRVGGKV LSLPKSVFVP DHTGAGQTMV DSGTQFTFLL GSVYTALRNE 300 FVLQTKPGLK LLDDPNFVFQ GAMDLCFQVP MDRLNRPVLP ALPAVTLMFR GAEMSVMGER 360 LLYRVAGMVR GSNQVYCFTF GNSDLLGIEA FVIGHYHQQN VWMEFDLEKS RVGVAQSSMK 420 GAEKVGGDGE RCKCSSLGFW WLCRISGLER RRFSADPNQS SLQAVMSFVF RGTRGDIESG 480 FPEFIPERRA MRVHTARSVN SNSLAFLVTV LLLFMILNSH QMSPNFLVSA FSECLWLVLG 540 VFLMATTLRM YATCQQLQAQ AQAHAAAASG LLGHTELRLH MPPSIALATR GRLQGLRLQL 600 ALLDREFDDL DYETLRALDS DNVPSASSMS EEEINALPVH KYKVVGPQNG ASSTQQASAS 660 VPAEKKQETA DGGSTKAIED ELTCSVCLEQ VNAGELIRSL PCLHQFHASC IDPWLKQQGT 720 CPVCKYRAGS GWQENGQGAA MDASYMSNQI EIFMESRNHH FLVISCAAQG HLNPSLQLAK 780 RLIDIGSSHV TFVTNIHGLT QIKSLPSLEG LSFASFSDGF DDGVHPANDP EHIMSELKRA 840 GSESLTALIE KISTSDEHGP ITFLIYTVLL PWAAEVASSF GIASAFLCIT SATSFAICGH 900 YFKDYYKSQS SLPFPSCITI DGLPPFASDE LPSYLLPTSP HVSILPTFQE HYQIWEKSPN 960 SCVLVNTFDG LEEAAIRDMR AHMNLITVGP LIRSAEVCCD LFDKSGDDYL QWLDTKADSS 1020 VVYVSFGSMV VLRSGQMEEM LHGLVDSGLP VLWVIRKSGN EGDQETENLI NNTLKKEQGL 1080 IVPWCSQVEV LSHKSVGCCV SHCGWNSTIE SLAAGVPVVG CPHFADQTTN AKLVEELWGS 1140 GVRARANEEG VIERAEIKRC LEVVMGDGVR GEEMRRNAQK WKSLAMKAVN ESGSSDDNLR 1200 NFVRSLA* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd05476 | pepsin_A_like_plant | 6.0e-64 | 53 | 416 | 372 | + Chroloplast Nucleoids DNA-binding Protease and Nucellin, pepsin-like aspartic proteases from plants. This family contains pepsin like aspartic proteases from plants including Chloroplast Nucleoids DNA-binding Protease and Nucellin. Chloroplast Nucleoids DNA-binding Protease catalyzes the degradation of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) in senescent leaves of tobacco and Nucellins are important regulators of nucellar cell's progressive degradation after ovule fertilization. Structurally, aspartic proteases are bilobal enzymes, each lobe contributing a catalytic Asp residue, with an extended active site cleft localized between the two lobes of the molecule. The N- and C-terminal domains, although structurally related by a 2-fold axis, have only limited sequence homology except the vicinity of the active site. This suggests that the enzymes evolved by an ancient duplication event. The enzymes specifically cleave bonds in peptides which have at least six residues in length with hydrophobic residues in both the P1 and P1' positions. The active site is located at the groove formed by the two lobes, with an extended loop projecting over the cleft to form an 11-residue flap, which encloses substrates and inhibitors in the active site. Specificity is determined by nearest-neighbor hydrophobic residues surrounding the catalytic aspartates, and by three residues in the flap. The enzymes are mostly secreted from cells as inactive proenzymes that activate autocatalytically at acidic pH. | ||
PLN02448 | PLN02448 | 8.0e-66 | 754 | 1204 | 485 | + UDP-glycosyltransferase family protein | ||
PLN02173 | PLN02173 | 4.0e-76 | 754 | 1203 | 473 | + UDP-glucosyl transferase family protein | ||
PLN02555 | PLN02555 | 1.0e-94 | 754 | 1206 | 478 | + limonoid glucosyltransferase | ||
PLN02152 | PLN02152 | 8.0e-114 | 760 | 1206 | 465 | + indole-3-acetate beta-glucosyltransferase |
Gene Ontology | |
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GO Term | Description |
GO:0004190 | aspartic-type endopeptidase activity |
GO:0006508 | proteolysis |
GO:0008152 | metabolic process |
GO:0016758 | transferase activity, transferring hexosyl groups |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2pq6_A | 8.00001e-42 | 756 | 1206 | 6 | 477 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt85h2- Insights Into The Structural Basis Of A Multifunctional (Iso) Flavonoid Glycosyltransferase |
PDB | 2vg8_A | 1e-37 | 755 | 1199 | 3 | 460 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt85h2- Insights Into The Structural Basis Of A Multifunctional (Iso) Flavonoid Glycosyltransferase |
PDB | 2vch_A | 1e-37 | 755 | 1199 | 3 | 460 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt85h2- Insights Into The Structural Basis Of A Multifunctional (Iso) Flavonoid Glycosyltransferase |
PDB | 2vce_A | 1e-37 | 755 | 1199 | 3 | 460 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |
PDB | 2c9z_A | 3e-35 | 817 | 1203 | 70 | 447 | A Chain A, Characterization And Engineering Of The Bifunctional N- And O-glucosyltransferase Involved In Xenobiotic Metabolism In Plants |