Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna28359.1-v1.0-hybrid |
Family | GT2 |
Protein Properties | Length: 1170 Molecular Weight: 131661 Isoelectric Point: 8.4096 |
Chromosome | Chromosome/Scaffold: 4 Start: 10231362 End: 10239055 |
Description | Cellulose-synthase-like C4 |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT2 | 194 | 368 | 1.7e-26 |
IPMCNEREVYEQSIAAACQMDWPRDRLLIQVLDDSDDIILQNLIQDEISEWSQKGINIIYRHRLIRTGYKAGNLKSAMGCEYVKDYEFVAIFDADFTPNP DFLKLTVPHFKGNPELGLVQARWSFVNKDENLLTRLQNINLCFHFEVEQQVNGVFLNFFGFNGTAGVWRIKALEE |
Full Sequence |
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Protein Sequence Length: 1170 Download |
MAPNNSVAVT IEKPNNSFSK TKSFEKEKAA STKQFTWVLL LKVNRIFACL SWLPMAFRKR 60 ITSSDMSDEE PRNRGKLYRF IQAFLVLSIV ALGVEVIAHY KNWNLNLVHH PWEVQGLLHW 120 SYMAWLSFRV DYIAPVAIFL SKFCIILFLI QSLDRLVLCL GCFWIKFKKI KPRIEPDAYD 180 VEDPSSFPMV LLQIPMCNER EVYEQSIAAA CQMDWPRDRL LIQVLDDSDD IILQNLIQDE 240 ISEWSQKGIN IIYRHRLIRT GYKAGNLKSA MGCEYVKDYE FVAIFDADFT PNPDFLKLTV 300 PHFKGNPELG LVQARWSFVN KDENLLTRLQ NINLCFHFEV EQQVNGVFLN FFGFNGTAGV 360 WRIKALEESG GWLERTTVED MDIAVRAHLN GWKFIFLNDV EALCELPESY ETYKKQQHRW 420 HSGPMQLFRL CLPAILTSKI SIFKKANLIF LFFLLRKLIL PFYSFTLFCI ILPLTMFIPE 480 AELPLWVICY VPIFMSFLNI LPSPKSFPFL VPYLLFENTM SVTKFNAMVS GLFQLGSSYE 540 WVVTKKTGRS SESDLFALAE RESSSEDKIL RRNSESGLEL LSKLKEQEVA PPKKKKKNGI 600 YRKELALAFL LLTASARSFL SAHGVHFYFL LFQGLSFLVV GLDLIASMEE EKDAFYVVRK 660 GDVVGIYKSL KDCQNQAGSS VCNPSVSVFK GYGLPKEAEE YLVSHGLKNA SYTISASDVK 720 DGLFGSLVAC PYQQPASSMV NSGFKIAPDQ LTRKRMPDVI NSGVNDPPQK RSLDPASSMV 780 NSGFKIAPHQ LTRMRLPDVV NSGVNDPPQR TLPDQSCILE FDGASKGNPG LSGAGAVLRA 840 EDGSVLHRLR EGVGIATNNV AEYRAVILGL KYALEKGYKH IRVQGDSKLV CCQIQGTWKT 900 KNQNMADLCQ VAKQLKDKFT SFQINHVLRE FNADADVLAN RAVNLRGKYT PSHYDCQVYV 960 KFAVIILNPK FAVKFLIRRR ETKEKDRAQR KQMATISVSP FSPLHPIPTL THSHSLSIPI 1020 PSPTLSFRNV SGSFRRLSSV RNTSSRRPTI VRSAEEDAPI EPVPEEEAGA EQPVSVPVSP 1080 SDTLTMFFQA DGTLSDAAVP AVTKALEETQ GITNLKVEVH EGIGIVELKK QTTVQATGVA 1140 SSLVEAIQSS GFKLQTLNLS FEEEEEIAV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR03030 | CelA | 2.0e-32 | 143 | 430 | 308 | + cellulose synthase catalytic subunit (UDP-forming). Cellulose synthase catalyzes the beta-1,4 polymerization of glucose residues in the formation of cellulose. In bacteria, the substrate is UDP-glucose. The synthase consists of two subunits (or domains in the frequent cases where it is encoded as a single polypeptide), the catalytic domain modelled here and the regulatory domain (pfam03170). The regulatory domain binds the allosteric activator cyclic di-GMP. The protein is membrane-associated and probably assembles into multimers such that the individual cellulose strands can self-assemble into multi-strand fibrils. | ||
COG1215 | COG1215 | 8.0e-37 | 132 | 507 | 378 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
cd09279 | RNase_HI_archaeal_like | 2.0e-46 | 817 | 942 | 127 | + RNAse HI family that includes Archaeal RNase HI. Ribonuclease H (RNase H) is classified into two evolutionarily unrelated families, type 1 (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type 2 (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. RNase H is involved in DNA replication, repair and transcription. RNase H is widely present in various organisms, including bacteria, archaea and eukaryotes and most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology, Type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site (DEDD) residues and have the same catalytic mechanism and functions in cells. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. Most archaeal genomes contain only type 2 RNase H (RNase HII); however, a few contain RNase HI as well. Although archaeal RNase HI sequences conserve the DEDD active-site motif, they lack other common features important for catalytic function, such as the basic protrusion region. Archaeal RNase HI homologs are more closely related to retroviral RNase HI than bacterial and eukaryotic type I RNase H in enzymatic properties. | ||
cd06421 | CESA_CelA_like | 2.0e-49 | 194 | 428 | 238 | + CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end. | ||
cd06437 | CESA_CaSu_A2 | 4.0e-103 | 188 | 424 | 237 | + Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex. Cellulose synthase (CESA) catalyzes the polymerization reaction of cellulose using UDP-glucose as the substrate. Cellulose is an aggregate of unbranched polymers of beta-1,4-linked glucose residues, which is an abundant polysaccharide produced by plants and in varying degrees by several other organisms including algae, bacteria, fungi, and even some animals. Genomes from higher plants harbor multiple CESA genes. There are ten in Arabidopsis. At least three different CESA proteins are required to form a functional complex. In Arabidopsis, CESA1, 3 and 6 and CESA4, 7 and 8, are required for cellulose biosynthesis during primary and secondary cell wall formation. CESA2 is very closely related to CESA6 and is viewed as a prime substitute for CESA6. They functionally compensate each other. The cesa2 and cesa6 double mutant plants were significantly smaller, while the single mutant plants were almost normal. |
Gene Ontology | |
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GO Term | Description |
GO:0003676 | nucleic acid binding |
GO:0004523 | ribonuclease H activity |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 4hg6_A | 3e-25 | 143 | 516 | 100 | 467 | B Chain B, Structure Of A Cellulose Synthase - Cellulose Translocation Intermediate |
PDB | 3hst_D | 9e-20 | 818 | 940 | 5 | 128 | B Chain B, N-Terminal Rnase H Domain Of Rv2228c From Mycobacterium Tuberculosis As A Fusion Protein With Maltose Binding Protein |
PDB | 3hst_B | 9e-20 | 818 | 940 | 5 | 128 | B Chain B, N-Terminal Rnase H Domain Of Rv2228c From Mycobacterium Tuberculosis As A Fusion Protein With Maltose Binding Protein |
PDB | 4e19_B | 3e-17 | 821 | 944 | 74 | 197 | A Chain A, Crystal Structure Of Rnase H1 From Halophilic Archaeon Halobacterium Salinarum Nrc-1 |
PDB | 4e19_A | 3e-17 | 821 | 944 | 74 | 197 | A Chain A, Crystal Structure Of Rnase H1 From Halophilic Archaeon Halobacterium Salinarum Nrc-1 |