Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna28878.1-v1.0-hybrid |
Family | CBM57 |
Protein Properties | Length: 917 Molecular Weight: 102254 Isoelectric Point: 6.3871 |
Chromosome | Chromosome/Scaffold: 3 Start: 6018250 End: 6028905 |
Description | hercules receptor kinase 2 |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
CBM57 | 287 | 441 | 7.3e-22 |
YRLNVGGSEVSPSQDSDLWRKWEVDTSYMITANAGLEIKNSSNITYSSVNESSVAPLLVYESARTMSNNEVLEKRFNMSWKFEVDPDFDYLVRLHFCELV FDKANQRIFRVYINNRTAADNFNVFVRAGGMNKAYHQDFFDVVSSKVKTLWIQLG |
Full Sequence |
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Protein Sequence Length: 917 Download |
MEKKRIERGA NREEEGEDGE ELQKRRRRQK EKKEAEAERE DDVVRMYNCY DLQADWVCGV 60 LKRKSQVGFK NQSLFIAVMV MKTCEAQSRS FLINCGTNSS VTVSGRKWVG DLTPNNNITL 120 SSNGIDAFTD IKSVDDSTYG VLYKTARMFS SSLNYTFQGV RGDYFVRLHF SPFSFDDYNV 180 NVSSFGVLAN GLKLVEKFVV PGEISQKNAY LQSSGSNLTS SLVKEYVLAI NRDALVIEFI 240 PDKEKFGFIN AIEIVPATEE LFAGSASKVG GNGANVNVSW QGIETMYRLN VGGSEVSPSQ 300 DSDLWRKWEV DTSYMITANA GLEIKNSSNI TYSSVNESSV APLLVYESAR TMSNNEVLEK 360 RFNMSWKFEV DPDFDYLVRL HFCELVFDKA NQRIFRVYIN NRTAADNFNV FVRAGGMNKA 420 YHQDFFDVVS SKVKTLWIQL GPDTAVGAAG TDALLNGLEI FKISRNGNLA FVDNYESSAN 480 SSKASSKTAI LWGAIGAGLA SVAILVTIVY YFCKCRREKL SDTKTTPPGW RPLFLVNSTV 540 NAKGSAGSKN QHGSVAPTRA GKRFLLPEIR AATNNFNESL VIGVGGFGKV YKGEIEDGTL 600 VAIKRSNPQS QQGLAEFETE IEMLSKLRHR HLVSLIGFCD EQNEMILVYE YMANGTLRSH 660 LFGSELPPLT WKQRVEACIG AARGLHYLHT GADRGIIHRD VKTTNILLDE NFVAKMSDFG 720 LSKTGPALDH THVSTAVKGS FGYLDPEYFR RQQLTEKSDV YSFGVVLFEA VCSRPVINPT 780 LPKDQINLAE WAMKWQRHRS LETIIDTHLE GNYCPESLKK FGDIAEKCLA DEGKSRPTMG 840 EVLWHLEYVL QLHEAWLRKN AGEHSFTSSQ GFGGLAVDEA EEREATSFDE ETGCSRESTS 900 RGFNESTTEG VEMVRK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam07714 | Pkinase_Tyr | 3.0e-51 | 581 | 846 | 279 | + Protein tyrosine kinase. | ||
smart00219 | TyrKc | 4.0e-52 | 581 | 846 | 272 | + Tyrosine kinase, catalytic domain. Phosphotransferases. Tyrosine-specific kinase subfamily. | ||
smart00221 | STYKc | 4.0e-53 | 581 | 846 | 275 | + Protein kinase; unclassified specificity. Phosphotransferases. The specificity of this class of kinases can not be predicted. Possible dual-specificity Ser/Thr/Tyr kinase. | ||
cd00192 | PTKc | 3.0e-53 | 581 | 847 | 289 | + Catalytic domain of Protein Tyrosine Kinases. Protein Tyrosine Kinase (PTK) family, catalytic domain. This PTKc family is part of a larger superfamily that includes the catalytic domains of protein serine/threonine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase (PI3K). PTKs catalyze the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in protein substrates. They can be classified into receptor and non-receptor tyr kinases. PTKs play important roles in many cellular processes including, lymphocyte activation, epithelium growth and maintenance, metabolism control, organogenesis regulation, survival, proliferation, differentiation, migration, adhesion, motility, and morphogenesis. Receptor tyr kinases (RTKs) are integral membrane proteins which contain an extracellular ligand-binding region, a transmembrane segment, and an intracellular tyr kinase domain. RTKs are usually activated through ligand binding, which causes dimerization and autophosphorylation of the intracellular tyr kinase catalytic domain, leading to intracellular signaling. Some RTKs are orphan receptors with no known ligands. Non-receptor (or cytoplasmic) tyr kinases are distributed in different intracellular compartments and are usually multi-domain proteins containing a catalytic tyr kinase domain as well as various regulatory domains such as SH3 and SH2. PTKs are usually autoinhibited and require a mechanism for activation. In many PTKs, the phosphorylation of tyr residues in the activation loop is essential for optimal activity. Aberrant expression of PTKs is associated with many development abnormalities and cancers. | ||
pfam12819 | Malectin_like | 5.0e-58 | 93 | 463 | 385 | + Carbohydrate-binding protein of the ER. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. The domain is found on a number of plant receptor kinases. |
Gene Ontology | |
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GO Term | Description |
GO:0004672 | protein kinase activity |
GO:0005524 | ATP binding |
GO:0006468 | protein phosphorylation |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2qkw_B | 0 | 563 | 855 | 28 | 319 | A Chain A, Structural Basis For Activation Of Plant Immunity By Bacterial Effector Protein Avrpto |
PDB | 3hgk_D | 0 | 563 | 855 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_C | 0 | 563 | 855 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_B | 0 | 563 | 855 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_A | 0 | 563 | 855 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |