Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna31189.1-v1.0-hybrid |
Family | AA7 |
Protein Properties | Length: 553 Molecular Weight: 61032.4 Isoelectric Point: 5.8561 |
Chromosome | Chromosome/Scaffold: 2 Start: 8130697 End: 8132355 |
Description | FAD-binding Berberine family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA7 | 66 | 537 | 0 |
LRFAEPTVPKPIAIILPESVEQIINSVYCSREVFLAIRVRCGGHSYEGTSSVAADGAPFVIIDMMNLNTVSVDLETEMAWVEGGATLGETYHAIAKASSV HGFSAGSCPTVGAGGHIAGGGFGLLSRKYGLAADNVVDALLIDADGRLLDRRGMGEDVFWAIRGGGGGVWGIVYAWKIQLLRVPQTVTVFVASRAGNKSH VANLVDKWQHVAPYLEDDFYISCFVGAGLPEAKTSGTTGISATFKGFYLGPRSSAMSTLDQVFPDIGIVKEDCKEMSWIESTVFFSGLGNGSSVSDLRNR YLENKGFFKAKSDYVRTAISHAGIRAAVEILEEEPKGYIILDPYGGIMHRISSESIAFPHRKGNLFTIQYLVEWKEEENYKRNEYVGWIRRLYNSMTPYV SWGPRTAYINYIDLDLGVMRLVETRVPTEKDKDAVEIARVWGEKYFLNNYDRLVRAKTIIDPRNVFSNQQGI |
Full Sequence |
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Protein Sequence Length: 553 Download |
MAISLRNQFP QFFTFMCILL PSLAEPTDEI TSCLTLHNIN NFTTFPNTEN DSDSYFKLLN 60 FSIQNLRFAE PTVPKPIAII LPESVEQIIN SVYCSREVFL AIRVRCGGHS YEGTSSVAAD 120 GAPFVIIDMM NLNTVSVDLE TEMAWVEGGA TLGETYHAIA KASSVHGFSA GSCPTVGAGG 180 HIAGGGFGLL SRKYGLAADN VVDALLIDAD GRLLDRRGMG EDVFWAIRGG GGGVWGIVYA 240 WKIQLLRVPQ TVTVFVASRA GNKSHVANLV DKWQHVAPYL EDDFYISCFV GAGLPEAKTS 300 GTTGISATFK GFYLGPRSSA MSTLDQVFPD IGIVKEDCKE MSWIESTVFF SGLGNGSSVS 360 DLRNRYLENK GFFKAKSDYV RTAISHAGIR AAVEILEEEP KGYIILDPYG GIMHRISSES 420 IAFPHRKGNL FTIQYLVEWK EEENYKRNEY VGWIRRLYNS MTPYVSWGPR TAYINYIDLD 480 LGVMRLVETR VPTEKDKDAV EIARVWGEKY FLNNYDRLVR AKTIIDPRNV FSNQQGIPPV 540 SYLSQASSTA AS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam08031 | BBE | 3.0e-14 | 472 | 538 | 67 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
COG0277 | GlcD | 7.0e-18 | 76 | 540 | 475 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
pfam01565 | FAD_binding_4 | 2.0e-21 | 76 | 215 | 141 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. |
Gene Ontology | |
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GO Term | Description |
GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
GO:0016491 | oxidoreductase activity |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3d2j_A | 0 | 5 | 552 | 1 | 531 | A Chain A, Crystal Structure (Monoclinic) Of Bee Venom Hyaluronidase |
PDB | 3d2h_A | 0 | 5 | 552 | 1 | 531 | A Chain A, Crystal Structure (Monoclinic) Of Bee Venom Hyaluronidase |
PDB | 3d2d_A | 0 | 5 | 552 | 1 | 531 | A Chain A, Structure Of Berberine Bridge Enzyme In Complex With (S)-Reticuline |
PDB | 4ec3_A | 0 | 24 | 552 | 2 | 512 | A Chain A, Structure Of Berberine Bridge Enzyme, H174a Variant In Complex With (S)-Reticuline |
PDB | 3gsy_A | 0 | 24 | 552 | 2 | 512 | A Chain A, Structure Of Berberine Bridge Enzyme In Complex With Dehydroscoulerine |