Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna32241.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 446 Molecular Weight: 51115.7 Isoelectric Point: 7.3622 |
Chromosome | Chromosome/Scaffold: 5 Start: 301714 End: 303051 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 33 | 385 | 0 |
CDDRWIHIRRLPSIFNLDLLSTCSGYPLFGDLCPFLPNHGLGHKTHNLSQSWYRTDSLIMELIFHRRMLEYPCLTSDPVQADAVYLPYYTGLDAMKYLYG PEVNSSADQGLELFRFLQDDMPEVWDRNSGHDHFMVLARPAWDFSQPLDSDPPTWGTSLLELPHFFNVTALTVESRAWPWQEQAVPYPTSFHPPNLSLLQ SWIQRARRSKRTCLMLFAGGGGVATGNPNIRRSIRNECVNSTRNVTHNVHGYLKLCDIVDCSNGICEHDPIRFMKPMLQASFCLQPPGDTPTRRSIFDSI LAGCIPVFFEEMSARTQYGWHLPEDQYPEFSVYIPKEDVVFKDTRILDVLRNI |
Full Sequence |
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Protein Sequence Length: 446 Download |
MASALLIPFF FFFLALVTSD PVIDQADTNP TECDDRWIHI RRLPSIFNLD LLSTCSGYPL 60 FGDLCPFLPN HGLGHKTHNL SQSWYRTDSL IMELIFHRRM LEYPCLTSDP VQADAVYLPY 120 YTGLDAMKYL YGPEVNSSAD QGLELFRFLQ DDMPEVWDRN SGHDHFMVLA RPAWDFSQPL 180 DSDPPTWGTS LLELPHFFNV TALTVESRAW PWQEQAVPYP TSFHPPNLSL LQSWIQRARR 240 SKRTCLMLFA GGGGVATGNP NIRRSIRNEC VNSTRNVTHN VHGYLKLCDI VDCSNGICEH 300 DPIRFMKPML QASFCLQPPG DTPTRRSIFD SILAGCIPVF FEEMSARTQY GWHLPEDQYP 360 EFSVYIPKED VVFKDTRILD VLRNIPRAKV RRMREKVLGL IPRIMYRKHG SSMGLRTKKD 420 AFDIAIEGVL QRVRSRVHRG QVFVL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-48 | 33 | 385 | 364 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |