| Basic Information | |
|---|---|
| Species | Citrus sinensis |
| Cazyme ID | orange1.1g002441m |
| Family | GT41 |
| Protein Properties | Length: 922 Molecular Weight: 102630 Isoelectric Point: 6.0592 |
| Chromosome | Chromosome/Scaffold: 00018 Start: 311563 End: 323563 |
| Description | Tetratricopeptide repeat (TPR)-like superfamily protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT41 | 363 | 854 | 0 |
| IKPNFSQSLNNLGVVYTVQGKMDAAAEMIEKAIAANPTYAEAYNNLGVLYRDAGSISLAIDAYEQCLKIDPDSRNAGQNRLLAMNYINEGHDDKLFEAHR DWGKRFMRLYSQYTSWDNTKDPERPLVIGYVSPDYFTHSVSYFIEAPLVYHDYQNYKVVVYSAVVKADAKTIRFREKVMKKGGIWRDIYGIDEKKVAAMV REDKIDILVELTGHTANNKLGMMACQPAPVQVTWIGYPNTTGLPTIDYRITDSLADPPETKQKHVEELIRLPECFLCYTPSPEAGPVCPTPALTNGFITF GSFNNLAKITPKVLQVWARILCAVPNSRLVVKCKPFCCDSVRHRFLSTLEQLGLESLRVDLLPLILLNHDHMQAYSLMDISLDTFPYAGTTTTCESLYMG VPCVTMAGSVHAHNVGVSLLTKVGLKHLIAKNEDEYVQLALQLASDVTALANLRMSLRDLMSKSPVCDGQNFALGLESTYRNMWHRYCKGDV | |||
| Full Sequence |
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| Protein Sequence Length: 922 Download |
| MAWVEKDVSN GRERDPVQDN GFLKGPQSLP GTSGSPVAVG STLKGFEGKD ALSYANILRS 60 RNKFVDALAL YEIVLEKDSG NVEAHIGKGI CLQMQNMGRL AFDSFSEAVK LDPQNACAHT 120 HCGILYKDEG RLVEAAESYH KALSADPSYK PAAECLAIVL TDLGTSLKLA GNTQDGIQKY 180 YEALKIDPHY APAYYNLGVV YSELMQYDTA LGCYEKAALE RPMYAEAYCN MGVIYKNRGD 240 LESAIACYER CLAVSPNFEI AKNNMAIALT DLGTKVKLEG DINQGVAYYK KALYYNWHYA 300 DAMYNLGVAY GEMLKFDMAI VFYELAFHFN PHCAEACNNL GVIYKDRDNL DKAVECYQMA 360 LSIKPNFSQS LNNLGVVYTV QGKMDAAAEM IEKAIAANPT YAEAYNNLGV LYRDAGSISL 420 AIDAYEQCLK IDPDSRNAGQ NRLLAMNYIN EGHDDKLFEA HRDWGKRFMR LYSQYTSWDN 480 TKDPERPLVI GYVSPDYFTH SVSYFIEAPL VYHDYQNYKV VVYSAVVKAD AKTIRFREKV 540 MKKGGIWRDI YGIDEKKVAA MVREDKIDIL VELTGHTANN KLGMMACQPA PVQVTWIGYP 600 NTTGLPTIDY RITDSLADPP ETKQKHVEEL IRLPECFLCY TPSPEAGPVC PTPALTNGFI 660 TFGSFNNLAK ITPKVLQVWA RILCAVPNSR LVVKCKPFCC DSVRHRFLST LEQLGLESLR 720 VDLLPLILLN HDHMQAYSLM DISLDTFPYA GTTTTCESLY MGVPCVTMAG SVHAHNVGVS 780 LLTKVGLKHL IAKNEDEYVQ LALQLASDVT ALANLRMSLR DLMSKSPVCD GQNFALGLES 840 TYRNMWHRYC KGDVPSLKRM EMLQQQVVSE EPSKFSEPTK IIFAKEGSPG SVMPNGFNQA 900 SPSMLNLSNI EENGVQLNQH Y* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam13844 | Glyco_transf_41 | 2.0e-17 | 488 | 637 | 151 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
| cd00189 | TPR | 6.0e-21 | 159 | 257 | 99 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
| pfam13844 | Glyco_transf_41 | 9.0e-24 | 660 | 846 | 187 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
| COG3914 | Spy | 1.0e-85 | 317 | 849 | 562 | + Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones] | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0005515 | protein binding |
| GO:0042802 | identical protein binding |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAX46402.1 | 0 | 1 | 915 | 1 | 916 | putative SPINDLY protein [Rosa luciae] |
| RefSeq | XP_002281883.1 | 0 | 1 | 915 | 1 | 913 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002308458.1 | 0 | 1 | 918 | 1 | 925 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002323412.1 | 0 | 1 | 901 | 1 | 906 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002530535.1 | 0 | 1 | 919 | 1 | 922 | o-linked n-acetylglucosamine transferase, ogt, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1w3b_B | 2e-37 | 89 | 441 | 41 | 378 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 1e-26 | 56 | 375 | 75 | 380 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 2e-18 | 56 | 313 | 143 | 386 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_B | 0.000000000007 | 52 | 240 | 207 | 388 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| PDB | 1w3b_A | 2e-37 | 89 | 441 | 41 | 378 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DY295408 | 401 | 430 | 827 | 0 |
| HO781209 | 361 | 493 | 853 | 0 |
| HO781209 | 113 | 398 | 510 | 0 |
| HO781209 | 67 | 214 | 278 | 0.0003 |
| HO781209 | 55 | 330 | 382 | 6 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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