Basic Information | |
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Species | Citrus sinensis |
Cazyme ID | orange1.1g004753m |
Family | GT41 |
Protein Properties | Length: 733 Molecular Weight: 82259.4 Isoelectric Point: 6.1744 |
Chromosome | Chromosome/Scaffold: 00018 Start: 311563 End: 323563 |
Description | Tetratricopeptide repeat (TPR)-like superfamily protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT41 | 192 | 665 | 0 |
QGKMDAAAEMIEKAIAANPTYAEAYNNLGVLYRDAGSISLAIDAYEQCLKIDPDSRNAGQNRLLAMNYINEGHDDKLFEAHRDWGKRFMRLYSQYTSWDN TKDPERPLVIGYVSPDYFTHSVSYFIEAPLVYHDYQNYKVVVYSAVVKADAKTIRFREKVMKKGGIWRDIYGIDEKKVAAMVREDKIDILVELTGHTANN KLGMMACQPAPVQVTWIGYPNTTGLPTIDYRITDSLADPPETKQKHVEELIRLPECFLCYTPSPEAGPVCPTPALTNGFITFGSFNNLAKITPKVLQVWA RILCAVPNSRLVVKCKPFCCDSVRHRFLSTLEQLGLESLRVDLLPLILLNHDHMQAYSLMDISLDTFPYAGTTTTCESLYMGVPCVTMAGSVHAHNVGVS LLTKVGLKHLIAKNEDEYVQLALQLASDVTALANLRMSLRDLMSKSPVCDGQNFALGLESTYRNMWHRYCKGDV |
Full Sequence |
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Protein Sequence Length: 733 Download |
MQPAYYNLGV VYSELMQYDT ALGCYEKAAL ERPMYAEAYC NMGVIYKNRG DLESAIACYE 60 RCLAVSPNFE IAKNNMAIAL TDLGTKVKLE GDINQGVAYY KKALYYNWHY ADAMYNLGVA 120 YGEMLKFDMA IVFYELAFHF NPHCAEACNN LGVIYKDRDN LDKAVECYQM ALSIKPNFSQ 180 SLNNLGVVYT VQGKMDAAAE MIEKAIAANP TYAEAYNNLG VLYRDAGSIS LAIDAYEQCL 240 KIDPDSRNAG QNRLLAMNYI NEGHDDKLFE AHRDWGKRFM RLYSQYTSWD NTKDPERPLV 300 IGYVSPDYFT HSVSYFIEAP LVYHDYQNYK VVVYSAVVKA DAKTIRFREK VMKKGGIWRD 360 IYGIDEKKVA AMVREDKIDI LVELTGHTAN NKLGMMACQP APVQVTWIGY PNTTGLPTID 420 YRITDSLADP PETKQKHVEE LIRLPECFLC YTPSPEAGPV CPTPALTNGF ITFGSFNNLA 480 KITPKVLQVW ARILCAVPNS RLVVKCKPFC CDSVRHRFLS TLEQLGLESL RVDLLPLILL 540 NHDHMQAYSL MDISLDTFPY AGTTTTCESL YMGVPCVTMA GSVHAHNVGV SLLTKVGLKH 600 LIAKNEDEYV QLALQLASDV TALANLRMSL RDLMSKSPVC DGQNFALGLE STYRNMWHRY 660 CKGDVPSLKR MEMLQQQVVS EEPSKFSEPT KIIFAKEGSP GSVMPNGFNQ ASPSMLNLSN 720 IEENGVQLNQ HY* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam13844 | Glyco_transf_41 | 2.0e-17 | 299 | 448 | 151 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
cd00189 | TPR | 1.0e-19 | 79 | 177 | 99 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
pfam13844 | Glyco_transf_41 | 8.0e-24 | 471 | 657 | 187 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
COG3914 | Spy | 3.0e-87 | 128 | 660 | 562 | + Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones] |
Gene Ontology | |
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GO Term | Description |
GO:0005515 | protein binding |
GO:0042802 | identical protein binding |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002281883.1 | 0 | 3 | 726 | 190 | 913 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281883.1 | 2e-35 | 21 | 273 | 99 | 356 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002530535.1 | 0 | 3 | 730 | 193 | 922 | o-linked n-acetylglucosamine transferase, ogt, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 4gz6_D | 1e-37 | 33 | 449 | 6 | 386 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
PDB | 4gz6_D | 4e-23 | 471 | 666 | 524 | 715 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
PDB | 4gz6_D | 0.000000005 | 4 | 118 | 45 | 152 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
PDB | 4gz6_D | 0.0000003 | 4 | 80 | 79 | 155 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
PDB | 4gz6_C | 1e-37 | 33 | 449 | 6 | 386 | A Chain A, The Superhelical Tpr Domain Of O-linked Glcnac Transferase Reveals Structural Similarities To Importin Alpha. |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DY295408 | 401 | 241 | 638 | 0 |
HO781209 | 361 | 304 | 664 | 0 |
HO781209 | 113 | 209 | 321 | 0 |
HO781209 | 67 | 25 | 89 | 0.0001 |
HO781209 | 55 | 141 | 193 | 4.3 |
Sequence Alignments (This image is cropped. Click for full image.) |
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